128排多层螺旋CT冠状动脉造影对显著冠状动脉狭窄诊断的准确性

Diagnostic accuracy of 128-row multidetector computed tomography coronary angiography in the diagnosis of significant coronary artery stenosis.

作者信息

Chaosuwannakit Narumol, Kiatchoosakun Songsak, Makarawate Pattarapong

机构信息

Radiology Department, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

J Med Assoc Thai. 2012 Dec;95(12):1548-55.

PMID:23390786

Abstract

OBJECTIVE

To evaluate the diagnostic accuracy of 128-multi detector row computed tomography coronary angiography (MDCTCA) with that of invasive conventional coronary angiography (CCA) in the diagnosis of coronary artery disease (CAD).

MATERIAL AND METHOD

Forty-two consecutive patients underwent both MDCTCA and CCA. All MDCTCA were evaluated for the presence of obstructive coronary stenosis by a blinded experts, and results were compared with quantitative CCA.

RESULTS

Three vessels and five segments were uninterpretable on MDCTCA. Therefore, 123 vessels and 558 segments from 42 patients were analyzed. Sensitivity, specificity and positive and negative predictive values of computed tomography for detecting detect > 50% luminal narrowing were 100%, 91%, 91%, and 100%, respectively, by patient, 98%, 98%, 96%, and 99%, respectively, by vessel, and 98%, 99%, 94%, and 99%, respectively, by segment. Moreover accuracy for detecting > 70% luminal narrowing were excellent by patient, vessel, and segment.

CONCLUSION

Noninvasive 128-detector row CT coronary angiography provides high diagnostic accuracy on per segment, vessel, and patient analysis.

摘要

目的

评估128排多层螺旋CT冠状动脉造影（MDCTCA）与有创传统冠状动脉造影（CCA）在诊断冠状动脉疾病（CAD）方面的诊断准确性。

材料与方法

42例连续患者同时接受了MDCTCA和CCA检查。所有MDCTCA图像均由一位不知情的专家评估是否存在阻塞性冠状动脉狭窄，并将结果与定量CCA结果进行比较。

结果

MDCTCA有3支血管和5个节段无法判读。因此，对42例患者的123支血管和558个节段进行了分析。CT检测管腔狭窄>50%时，按患者计算的灵敏度、特异度、阳性预测值和阴性预测值分别为100%、91%、91%和100%；按血管计算分别为98%、98%、96%和99%；按节段计算分别为98%、99%、94%和99%。此外，在检测管腔狭窄>70%方面，按患者、血管和节段计算的准确性均极佳。