64层CT冠状动脉造影的准确性：我们的初步经验。

Accuracy of 64-slice CT coronary angiography: our initial experience.

作者信息

Prakash Ashutosh, Ahlawat Kulbir, Kaul U A, Tyagi Sanjay, Aggarwal Bharat, Rajan Sriram, Kathuria Sanjeev

机构信息

Diwan Chand Imaging Research Center, New Delhi, India.

出版信息

Indian Heart J. 2008 Jul-Aug;60(4):287-95.

PMID:19242004

Abstract

OBJECTIVE

The objective of our study was to evaluate the diagnostic accuracy of 64-slice computed tomography coronary angiography to detect haemodynamically significant stenosis (>50% luminal narrowing) in comparison to invasive coronary angiography and further analyze the result accounting for heart rate, coronary calcification and location of lesion in the coronary tree.

METHODS AND RESULTS

Forty patients (39 male, 1 female; mean age 50.9 years) underwent both CT coronary angiography and invasive coronary angiography with in a gap of one day. All vessels were included in the study and no patient was excluded due to high heart rate. On per-segment based analysis with invasive coronary angiography as the gold standard, CT coronary angiography correctly identified 62 out of 78 significant stenoses with an overall sensitivity of 79.5% (62 of 78), specificity of 98.5% (532 of 540), positive predictive value of 88.6% (62 of 70) and negative predictive value of 97.1% (532 of 548).

CONCLUSION

Our result suggests that 64-slice CT coronary angiography has high diagnostic accuracy to detect haemodynamically significant stenosis.

摘要

目的

我们研究的目的是评估64层计算机断层扫描冠状动脉造影术检测血流动力学显著狭窄（管腔狭窄>50%）的诊断准确性，并与有创冠状动脉造影术进行比较，进一步分析结果，同时考虑心率、冠状动脉钙化以及冠状动脉树中病变的位置。

方法与结果

40例患者（39例男性，1例女性；平均年龄50.9岁）在一天的间隔内先后接受了CT冠状动脉造影和有创冠状动脉造影。所有血管均纳入研究，无患者因心率过快而被排除。以有创冠状动脉造影为金标准进行基于节段的分析，CT冠状动脉造影在78处显著狭窄中正确识别出62处，总体敏感性为79.5%（78处中的62处），特异性为98.5%（540处中的532处），阳性预测值为88.6%（70处中的62处），阴性预测值为97.1%（548处中的532处）。