Electrochemical recognition for carboxylic acids based on multilayer architectures of β-cyclodextrin and methylene blue/reduce-graphene interface on glassy carbon electrodes.

A chiral interface has been designed for specific recognition of carboxylic acids using multilayer architectures of β-cyclodextrin (β-CD) and methylene blue/reduce-graphene (MB@rGO) on glassy carbon electrodes. The advantages of β-CD as a chiral selector and MB@rGO composite as an electrochemical indicator were perfectly presented in this novel interface. It displayed good redox signal for sensing chiral target with high sensitivity and conductivity. Enormous signal differences were obtained after adsorption of target L isomer, due to strong blocking of the electron transfer process of methylene blue. Meanwhile mandelic acid was found to be the best chiral guest and obtained more effective chiral recognition.