Rothenbühler J M, Beglinger C, Meyer B, Marx A, Ackermann C, Stalder G A, Harder F
Allgemeinchirurgische Klinik, Departement Chirurgie, Kantonsspital Basel.
Schweiz Med Wochenschr. 1990 Apr 21;120(16):593-5.
43 patients with symptomatic gallbladder stones were treated by extracorporeal shockwave lithotripsy and oral bile acids. In all patients the stones were successfully fragmented during the first lithotripsy session. 33 patients underwent 2-4 treatment sessions. In 16 out of 43 patients the stones disappeared within 7.9 months. The rate of stone dissolution was dependent on the number and size of stones. 3 patients required surgery because of frequent colic in one case, cholecystitis in one case and lack of cooperation in one case. No important side effects were noted except mild pancreatitis 3 weeks after lithotripsy in one patient. Results at this center of extracorporeal shockwave lithotripsy combined with oral bile acids indicate that this treatment may become an alternative to cholecystectomy in patients with a small number (less than 3) of stones not exceeding 30 mm in diameter.
43例有症状的胆囊结石患者接受了体外冲击波碎石术及口服胆汁酸治疗。所有患者在首次碎石治疗期间结石均成功破碎。33例患者接受了2至4次治疗。43例患者中有16例结石在7.9个月内消失。结石溶解率取决于结石的数量和大小。3例患者因频繁绞痛(1例)、胆囊炎(1例)及不配合(1例)而需要手术。除1例患者在碎石术后3周出现轻度胰腺炎外,未观察到重要的副作用。该中心体外冲击波碎石术联合口服胆汁酸的治疗结果表明,对于结石数量少(少于3枚)且直径不超过30毫米的患者,这种治疗可能成为胆囊切除术的替代方法。