Department of Ophthalmology, Myongji Hospital, Kwandong University College of Medicine, Goyang, Gyeonggi, Korea.
Am J Ophthalmol. 2013 May;155(5):823-8. doi: 10.1016/j.ajo.2012.12.011. Epub 2013 Feb 6.
To evaluate and report the results of a 3-year study investigating argon laser photoablation of superficial conjunctival nevus.
Retrospective, interventional case series.
The medical charts of patients referred to our clinic for the removal of a conjunctival nevus were reviewed. Argon laser photoablation of superficial conjunctival nevi was performed for 230 patients during the period from March 2006 to February 2009. The clinical course, complications, and recurrence rates were evaluated.
The mean follow-up period was 71.29 ± 19.51 months (range, 36-100 months). The horizontal and vertical diameters of conjunctival nevi were 4.53 ± 1.85 mm and 3.41 ± 1.62 mm, respectively. Most nevi were faintly pigmented and located on the nasal bulbar conjunctiva. The argon laser spot size was 200 μm; its duration was 0.1 second; and the power was 321.50 ± 9.23 mW. One session was required to completely remove the nevus in 212 eyes (81%). The total number of laser spots that were required to remove 1 nevus was 107.83 ± 33.68 (range, 53-172) for cases in which the horizontal and vertical diameters were <4 mm. In all cases, the laser procedure resulted in complete removal of the conjunctival nevus. There were no significant complications, such as infection, corneal damage, or permanent injection.
Argon laser photoablation could be a safe and effective treatment for benign superficial conjunctival pigmentation. This method is especially helpful for large conjunctival nevi, for which surgical excision would be impossible.
评估并报告一项为期 3 年的研究结果,该研究调查了氩激光光凝治疗浅层结膜色素痣。
回顾性、干预性病例系列研究。
回顾性分析 2006 年 3 月至 2009 年 2 月期间因结膜色素痣就诊于我院的患者的病历。对 230 例浅层结膜色素痣患者行氩激光光凝治疗。评估临床病程、并发症和复发率。
平均随访时间为 71.29 ± 19.51 个月(范围 36-100 个月)。结膜色素痣的水平和垂直直径分别为 4.53 ± 1.85mm 和 3.41 ± 1.62mm。大多数色素痣呈淡褐色,位于鼻侧球结膜。氩激光光斑大小为 200μm;持续时间为 0.1 秒;功率为 321.50 ± 9.23mW。212 只眼(81%)一次治疗即可完全去除色素痣。对于水平和垂直直径均<4mm 的色素痣,完全去除 1 个色素痣需要的激光点数为 107.83 ± 33.68(范围 53-172)。所有病例均完全去除了结膜色素痣,无明显并发症,如感染、角膜损伤或永久性注射。
氩激光光凝治疗良性浅层结膜色素沉着是一种安全有效的治疗方法。对于手术切除困难的较大结膜色素痣,该方法尤其有用。