Vision Health Research Center, Semnan University of Medical Science, Semnan, Iran.
Iran J Med Sci. 2023 Jan;48(1):85-90. doi: 10.30476/IJMS.2022.93665.2494.
Conjunctival nevi (CN) are common benign ocular tumors. Given their low risk of malignancy, surgical removal of nevi is primarily requested by patients. Herein, we introduce Atmospheric Low-temperature Plasma (ALTP) as a novel noninvasive method for the removal of CN.
A clinical case series was conducted from 2020 to 2021 at the Vision Health Ophthalmic Center in Tehran, Iran. CN in one of the eyes of seven patients was treated. In all patients, the benignity of CN was confirmed by ocular oncologists. The white handpiece of the Plexr device, which generates plasma with the lowest output, was used to apply plasma spots on the nevi. In addition, the Ocular Surface Disease Index (OSDI) questionnaire was completed by all patients before and six months after the treatment.
In all patients, the nevi outside the limbus area completely disappeared. The mean size of pre- and post-operative nevi was 3.89×11.7 and 0.54×1.69 mm, respectively. Results of the OSDI questionnaire showed significantly lower scores after the surgery in all patients.
The ALTP method is a simple, cost-effective, and office-based surgery to remove CN safely and effectively.
结膜痣（CN）是常见的良性眼部肿瘤。鉴于其恶性转化风险低，手术切除主要是由患者提出的。在此，我们介绍大气低温等离子体（ALTP）作为一种去除 CN 的新型非侵入性方法。
2020 年至 2021 年，在伊朗德黑兰的 Vision Health 眼科中心进行了一项临床病例系列研究。对七名患者的一只眼睛中的 CN 进行了治疗。在所有患者中，眼肿瘤科医生均确认 CN 为良性。使用产生最低输出等离子体的 Plexr 设备的白色手柄在痣上施加等离子斑。此外，所有患者在治疗前和治疗后六个月都填写了眼表疾病指数（OSDI）问卷。
在所有患者中，位于角膜缘区域以外的痣完全消失。术前和术后痣的平均大小分别为 3.89×11.7 和 0.54×1.69mm。OSDI 问卷的结果显示，所有患者术后得分均显著降低。
ALTP 方法是一种简单、具有成本效益且基于办公室的手术，可以安全有效地去除 CN。
