Park Young Min, Lee Ji-Eun, Lee Jong Soo
Department of Ophthalmology, Pusan National University School of Medicine and Medical Research Institute, Yangsan Pusan National University Hospital, Yangsan, South Korea.
Department of Ophthalmology, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital, 11, Samjeongja-ro, Seongsan-gu, Changwon-si, Gyeongsangnam-do, 51472, South Korea.
Lasers Med Sci. 2016 Jul;31(5):1037-9. doi: 10.1007/s10103-016-1915-x. Epub 2016 Feb 25.
This study reports the efficacy and safety of Pattern Scan Laser (PASCAL) photocoagulation in the removal of superficial conjunctival nevi. Superficial conjunctival nevi were removed from 10 eyes of 10 patients using PASCAL. The laser spots were 200 μm in size, and the power delivered ranged from 250 to 300 mW. The duration of the laser pulse was kept at the minimum needed for adequate lesion removal. The duration of the laser pulse administered to the patients varied from 100 to 200 ms. Complete removal of the conjunctival nevus was observed in all the patients after PASCAL photocoagulation. Six months after treatment, complete re-epithelialization of the overlying conjunctiva was noted. No signs of recurrence or scarring were found in any of the patients during the follow-up period. Pure thermal denaturation is the main mechanism of PASCAL photocoagulation for removal of superficial conjunctival nevi. PASCAL can be considered as an alternative to conventional argon laser treatment or surgery.
本研究报告了模式扫描激光（PASCAL）光凝术在去除浅表性结膜痣方面的疗效和安全性。使用PASCAL对10例患者的10只眼睛进行了浅表性结膜痣切除。激光光斑大小为200μm，输出功率范围为250至300mW。激光脉冲持续时间保持在充分去除病变所需的最短时间。给予患者的激光脉冲持续时间为100至200ms。PASCAL光凝术后所有患者的结膜痣均被完全切除。治疗6个月后，可见上方结膜完全重新上皮化。随访期间所有患者均未发现复发或瘢痕形成迹象。纯热变性是PASCAL光凝术去除浅表性结膜痣的主要机制。PASCAL可被视为传统氩激光治疗或手术的替代方法。
