Takeda Y, Kuroda M, Suzuki A
Department of Oral Pathology, School of Dentistry, Iwate Medical University, Morioka, Japan.
Acta Pathol Jpn. 1990 Feb;40(2):143-8. doi: 10.1111/j.1440-1827.1990.tb01553.x.
A review of the literature shows that unilateral benign salivary gland tumors of different histologic types in a single gland are so rare as to be curiosities, and all of such reported tumors have arisen in the parotid gland. The present paper reports a case of synchronous benign epithelial tumors of different histologic type arising in the palatal minor salivary gland of a 57-year-old woman who had first noted palatal swelling about 20 years previously. Pathologically, the lesion was composed of two distinct tumors, pleomorphic adenoma and lumenless trabecular adenoma, which were sharply demarcated from each other by a thin layer of fibrous connective tissue. Foci of tumor cells with cellular atypia were seen in some areas of the pleomorphic adenoma. The present case is thought to represent a previously undescribed component within the spectrum of minor salivary gland tumors.
文献综述显示，单个腺体中不同组织学类型的单侧良性涎腺肿瘤极为罕见，堪称罕见病例，且所有此类报道的肿瘤均发生于腮腺。本文报告一例发生于一名57岁女性腭部小涎腺的不同组织学类型的同步良性上皮性肿瘤病例，该患者约20年前首次发现腭部肿胀。病理检查显示，病变由两种不同的肿瘤组成，即多形性腺瘤和无腔小梁腺瘤，二者被一层薄的纤维结缔组织清晰分隔。在多形性腺瘤的某些区域可见具有细胞异型性的肿瘤细胞灶。本病例被认为代表了小涎腺肿瘤谱系中一种此前未描述的成分。
