Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia.
ENT Department, Sidi Bouzid Hospital, Sidi Bouzid, Tunisia.
F1000Res. 2024 Jun 28;13:243. doi: 10.12688/f1000research.146682.2. eCollection 2024.
Pleomorphic adenomas (PA) are the most prevalent benign salivary gland neoplasms. They may occur at any age, with a peak incidence between 40 and 60 years of age. They are more commonly observed in females (60%). These tumors can arise in both the major and minor salivary glands. Approximately 80% of these tumors are diagnosed in the parotid gland, whereas 10% arise in the minor salivary glands, mainly affecting the palates, followed by the lips and cheeks. This report describes two cases of unusual lesions that were diagnosed as (PA) in the minor salivary glands in our department via a review of the relevant literature. The first case involved an 83-year-old man who presented with a slow-growing swelling on the right side of the upper lip, and the second case involved a 45-year-old woman who presented with a slow-growing lesion on the palate. The presence of PA was confirmed histopathologically after surgical resection. Although relatively rare, PA is a benign lesion, the diagnosis of which must be known for appropriate therapeutic management.
多形性腺瘤（PA）是最常见的良性涎腺肿瘤。它们可发生于任何年龄，发病高峰为 40-60 岁，女性多见（60%）。这些肿瘤可发生于大、小涎腺，80%的肿瘤发生于腮腺，10%发生于小涎腺，主要累及腭部，其次为唇和颊部。本报告通过复习相关文献，描述了我科经病理证实的 2 例发生于小涎腺的罕见病例。第 1 例为 83 岁男性，右上唇缓慢生长性肿胀；第 2 例为 45 岁女性，腭部缓慢生长性病变。手术切除后组织病理学证实为 PA。PA 虽属良性病变，但较为罕见，了解其诊断对恰当的治疗管理至关重要。
