手性半胱氨酸保护金纳米簇的简便制备及其在细胞成像中的应用。
Facile preparation of chiral penicillamine protected gold nanoclusters and their applications in cell imaging.
机构信息
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, Jilin, PR China.
出版信息
Chem Commun (Camb). 2013 Mar 21;49(23):2302-4. doi: 10.1039/c3cc00200d.
PMID:23396404
Abstract
A facile synthesis of chiral penicillamine protected Au nanoclusters with different optical properties has been reported. We have for the first time observed the reversal of CD signals after the scaffolds adsorbed onto the surface of Au NCs. Such Au NCs are utilized for bioimaging due to their low cytotoxicity and stable fluorescence emission.
摘要
一种简便的手性半胱氨酸保护的金纳米簇的合成方法，具有不同的光学性质。我们首次观察到支架吸附到 Au NCs 表面后 CD 信号的反转。由于其低细胞毒性和稳定的荧光发射，这些 Au NCs 可用于生物成像。
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