Vallejo Herrador J, Rodríguez Luna J M, Fernández Fernández A, Perales Cabanas L, Romero Maroto J, Pérez Bustamante I
Servicio de Urología, Hospital Ramón y Cajal, Universidad de Alcalá de Henares, Madrid.
Actas Urol Esp. 1990 Jan-Feb;14(1):23-7.
We study the effect of oxybutynin chloride (Ditropan) in a random sample of 24 children with ages ranging from 5 to 14 years, diagnosed as having vesical instability from both the clinical and urodynamic standpoints. These effects were evaluated after a period of treatment that ranged from 10 to 36 months (x = 20). We obtained overall clinical improvement in 87.5%, and improvement of urodynamic alterations in 83.3% of the patients. We single out the beneficial effect of oxybutynin chloride with prolonged treatments, in instability of the detrusor, as well as its good tolerance.
我们对24名年龄在5至14岁之间、从临床和尿动力学角度均被诊断为膀胱不稳定的儿童进行了随机抽样研究，以探讨氯化奥昔布宁（得妥）的疗效。在为期10至36个月（平均20个月）的治疗期后对这些疗效进行了评估。我们发现87.5%的患者临床症状整体改善，83.3%的患者尿动力学改变得到改善。我们特别指出了氯化奥昔布宁在长期治疗中对逼尿肌不稳定的有益作用及其良好的耐受性。
