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Th17 cells, pathogenic or not? TGF-β3 imposes the embargo.

作者信息

Sharma Meenu, Kaveri Srini V, Bayry Jagadeesh

机构信息

Unité 872, Institut National de la Santé et de la Recherche Médicale, Paris, France.

出版信息

Cell Mol Immunol. 2013 Mar;10(2):101-2. doi: 10.1038/cmi.2012.72. Epub 2013 Feb 11.

Abstract
摘要

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本文引用的文献

1
Induction and molecular signature of pathogenic TH17 cells.
Nat Immunol. 2012 Oct;13(10):991-9. doi: 10.1038/ni.2416. Epub 2012 Sep 9.
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Th17 cells: biology, pathogenesis of autoimmune and inflammatory diseases, and therapeutic strategies.
Am J Pathol. 2012 Jul;181(1):8-18. doi: 10.1016/j.ajpath.2012.03.044. Epub 2012 May 26.
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Regulation of TH17 cell differentiation by innate immune signals.
Cell Mol Immunol. 2012 Jul;9(4):287-95. doi: 10.1038/cmi.2012.10. Epub 2012 Apr 16.
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Control of TH17 cells occurs in the small intestine.
Nature. 2011 Jul 17;475(7357):514-8. doi: 10.1038/nature10228.
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Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4.
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T-bet is essential for encephalitogenicity of both Th1 and Th17 cells.
J Exp Med. 2009 Jul 6;206(7):1549-64. doi: 10.1084/jem.20082584. Epub 2009 Jun 22.
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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.
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