Belotti Laura Maria Beatrice, Bartoli Simona, Trombetti Susanna, Montella Maria Teresa, Toni Aldo, De Palma Rossana
Regional Agency for Health and Social Care of Emilia-Romagna, Bologna, Italy.
Hip Int. 2013 Jan-Feb;23(1):15-21. doi: 10.5301/HIP.2013.10717.
Hip fracture is becoming a major public health concern, with associated mortality and morbidity particularly in the elderly. This study aims to investigate factors (i.e. patient factors and hospital variables) associated with increased risk for delaying surgery after hip fractures, and to assess whether and to what extent timing was associated with mortality risk. All patients aged 65 and over, resident in Emilia Romagna Region (Italy) and admitted to hospital for hip fracture (2009 - 2010) were selected. Data on surgical delay were adjusted using multilevel logistic regression model. A Cox proportional hazard model was fitted to a propensity score matched sample to assess mortality between delayed and early treated patients. Of the 10, 995 patients included (mean age: 83.3 years), 44.9% underwent surgery within 2 days. Significant risk factors for delayed surgery were: gender (OR: 1.16), comorbidity (OR: 1.29), anticoagulant (OR: 7.64) ,antiplatelet medication (OR: 2.43) , type of procedure (OR: 1.37) and day of admission (OR: Thu-Fri: 6.05; Sat-Sun: 1.17). Type of hospital and annual volume of hip fracture surgeries were not sufficient to explain hospital variability. A significant difference in mortality rate between early and delayed surgery emerged six months post surgery.
髋部骨折正成为一个重大的公共卫生问题,尤其是在老年人中,与之相关的死亡率和发病率都很高。本研究旨在调查与髋部骨折后手术延迟风险增加相关的因素(即患者因素和医院变量),并评估手术时机是否以及在何种程度上与死亡风险相关。选取了所有年龄在65岁及以上、居住在意大利艾米利亚-罗马涅地区且因髋部骨折于2009年至2010年入院的患者。使用多水平逻辑回归模型对手术延迟数据进行校正。对倾向得分匹配样本拟合Cox比例风险模型,以评估延迟治疗患者和早期治疗患者之间的死亡率。在纳入的10995例患者(平均年龄:83.3岁)中,44.9%在2天内接受了手术。手术延迟的显著风险因素包括:性别(比值比:1.16)、合并症(比值比:1.29)、抗凝剂(比值比:7.64)、抗血小板药物(比值比:2.43)、手术类型(比值比:1.37)和入院日期(比值比:周四至周五:6.05;周六至周日:1.17)。医院类型和髋部骨折手术的年手术量不足以解释医院之间的差异。术后六个月,早期手术和延迟手术的死亡率出现了显著差异。