King Ewa, Shih Grace, Ratnapradipa Dhitinut, Quilliam Daniela N, Morton John, Magee Susanna R
State Health Laboratories, Rhode Island Department of Health, Providence, RI 02904, USA.
J Environ Health. 2013 Jan-Feb;75(6):38-43.
The study described in this article aimed to determine if measurable levels of mercury, lead, and cadmium are detected in the umbilical cord blood specimens collected in a community hospital in Rhode Island and if prenatal exposure correlates with prematurity or fetal growth indicators. Total mercury, lead, and cadmium concentrations were measured in 538 specimens of cord blood and correlated with demographic characteristics and pregnancy outcomes for each mother-infant pair. Lead concentrations determined in the cord blood of Rhode Island women (geometric mean 0.99 microg/dL) were similar to those reported in U.S. biomonitoring studies. The overall geometric mean for mercury concentration (0.52 microg/L) was slightly lower than in other comparable studies. Cadmium concentrations were generally below the limit of detection. A statistically significant correlation was detected between elevated mercury concentrations and racial and ethnic characteristics of the study participants. Non-Hispanic African-American mothers were 9.6 times more likely to have a mercury concentration > or = 5.8 microg/L compared to women of other racial/ethnic backgrounds. No association was detected between elevated mercury levels and adverse birth outcomes.
本文所述研究旨在确定在罗德岛一家社区医院采集的脐带血样本中是否能检测到可测量水平的汞、铅和镉，以及产前暴露是否与早产或胎儿生长指标相关。对538份脐带血样本中的总汞、铅和镉浓度进行了测量，并将其与每对母婴的人口统计学特征和妊娠结局相关联。罗德岛女性脐带血中测得的铅浓度（几何平均值为0.99微克/分升）与美国生物监测研究报告的浓度相似。汞浓度的总体几何平均值（0.52微克/升）略低于其他可比研究。镉浓度一般低于检测限。研究参与者汞浓度升高与种族和民族特征之间存在统计学上的显著相关性。与其他种族/民族背景的女性相比，非西班牙裔非裔美国母亲的汞浓度≥5.8微克/升的可能性高9.6倍。未检测到汞水平升高与不良出生结局之间存在关联。
