Soong Y K, Tseng R, Liu C, Lin P W
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taipei, Taiwan R.O.C.
J Formos Med Assoc. 1991 Jan;90(1):59-65.
In this study the levels of lead, arsenic, cadmium and mercury were measured by the method of graphite-furnace atomic absorption spectrophotometry in paired maternal and fetal cord blood (n = 168) collected from three cities in Taiwan, (Kaohsiung, Taipei and Keelung). The mean values of those heavy metals were within normal limits. There was no difference in levels by maternal parity or fetal sex. The mean value for the level of lead in maternal blood was 64.8 micrograms/L, and 40.9 micrograms/L for the umbilical-cord blood; comparing the three locations by ANOVA analysis, there was no difference in maternal or fetal blood levels. Mean maternal As concentrations (6.8 +/- 0.58 micrograms/L) and umbilical cord blood levels (7.9 +/- 0.67 micrograms/L) were within reference levels. The mean Cd concentrations in maternal blood were (1.30 micrograms/L) significantly higher than that of the umbilical-cord blood concentrations (0.78 micrograms/L). The maternal Cd concentrations (1.62 micrograms/L) of Kaohsiung were significantly higher than that (1.24 micrograms/L) of Taipei. The fetal Cd concentrations of Kaohsiung (1.04 micrograms/L) were also significantly higher than those (0.7 micrograms/L, 0.6 micrograms/L) of Taipei and Keelung. The mean umbilical-cord blood Hg concentration (28.8 micrograms/L) was higher than that (19.4 micrograms/L) of maternal blood. The maternal Hg concentrations of Taipei were significantly higher than those of Keelung. The fetal Hg concentrations (28.8 micrograms/L) of Taipei were also marginally higher than that of Keelung and Kaohsiung.
在本研究中，采用石墨炉原子吸收分光光度法，对从台湾三个城市（高雄、台北和基隆）采集的168对母婴脐带血中的铅、砷、镉和汞水平进行了测定。这些重金属的平均值均在正常范围内。重金属水平在产妇胎次或胎儿性别方面无差异。产妇血液中铅水平的平均值为64.8微克/升，脐带血中为40.9微克/升；通过方差分析比较三个地点，产妇或胎儿血液水平无差异。产妇砷的平均浓度（6.8±0.58微克/升）和脐带血水平（7.9±0.67微克/升）均在参考水平内。产妇血液中镉的平均浓度（1.30微克/升）显著高于脐带血浓度（0.78微克/升）。高雄产妇的镉浓度（1.62微克/升）显著高于台北（1.24微克/升）。高雄胎儿的镉浓度（1.04微克/升）也显著高于台北（0.7微克/升）和基隆（0.6微克/升）。脐带血汞的平均浓度（28.8微克/升）高于产妇血液中的浓度（19.4微克/升）。台北产妇的汞浓度显著高于基隆。台北胎儿的汞浓度（28.8微克/升）也略高于基隆和高雄。
