孕期吸烟的尼古丁咀嚼胶治疗试验参与者中重度抑郁症和创伤后应激障碍。
Major depression and PTSD in pregnant smokers enrolled in nicotine gum treatment trial.
机构信息
Department of Medicine, University of Connecticut School of Medicine, Farmington, Connecticut, USA.
出版信息
Am J Addict. 2013 Jan;22(1):54-9. doi: 10.1111/j.1521-0391.2013.12029.x.
BACKGROUND AND OBJECTIVES
Pregnant women face considerable barriers to smoking cessation. The purpose of this study was to determine the prevalence of major depressive disorder (MDD) and post-traumatic stress disorder (PTSD) and response to smoking cessation treatment in pregnant smokers participating in a randomized, placebo-controlled trial of nicotine gum.
METHODS
Participants were 194 low-income, ethnically diverse pregnant smokers.
RESULTS
Utilizing a structured interview, 45% and 18% of the subjects met criteria for a lifetime diagnosis of MDD and PTSD, respectively. There was no difference in response to treatment, based on the presence of either of these psychiatric disorders.
CONCLUSIONS
Cumulatively, these findings provide evidence of the high degree of unmet mental health needs in pregnant smokers.
SCIENTIFIC SIGNIFICANCE
Pregnant women with a history of MDD and PTSD appear to be as likely to benefit from smoking cessation treatment as those without such a history.
背景与目的
孕妇在戒烟方面面临着相当大的障碍。本研究的目的是确定参加尼古丁口香糖随机、安慰剂对照试验的孕妇吸烟者中重度抑郁症（MDD）和创伤后应激障碍（PTSD）的患病率，以及对戒烟治疗的反应。
方法
参与者为 194 名低收入、种族多样化的孕妇吸烟者。
结果
利用结构化访谈，45%和 18%的受试者分别符合 MDD 和 PTSD 的终身诊断标准。基于这些精神疾病的存在，治疗反应没有差异。
结论
这些发现共同证明了孕妇的心理健康需求未得到满足的程度很高。
科学意义
有 MDD 和 PTSD 病史的孕妇似乎与没有此类病史的孕妇一样有可能从戒烟治疗中受益。
Zotero 插件