Britton Geraldine R, James Gary D, Collier Rosemary, Sprague Lori Marie, Brinthaupt JoAnne
Binghamton University, Decker School of Nursing, PO Box 6000, Binghamton, NY 13902-6000, USA.
Ann Hum Biol. 2013 May;40(3):256-65. doi: 10.3109/03014460.2012.761727. Epub 2013 Feb 11.
The purpose of this study was to evaluate the perinatal outcomes of rural pregnant smokers enrolled in the Smoke Free Baby & Me trial.
Data on smoking status and other pre-natal variables were collected during pregnancy. Outcomes were retrieved from a review of hospital records of 161 singleton births (79 from the control group, 82 from the intervention group).
The results show that, after adjusting for gender and gestational age, the more self-reported cigarettes at the first pre-natal visit, the less the infant birth weight (p = 0.033), the less maternal weight gain (p = 0.042) and the shorter the labour length (p = 0.041). Infants of women with positive urinary cotinine at the first pre-natal visit in the intervention group had higher 1 minute Apgar scores than those with negative cotinine (p = 0.022). Smokers also had a preponderance of male infants (64% vs 36%), while non-smokers had more females (59% vs 41%) (p = 0.006).
Smoking during pregnancy affects perinatal outcomes. Assuming a foetal origin of chronic disease morbidity, implementing smoking cessation during pregnancy would not only improve maternal and foetal health, but also might contribute to an improvement in the incidence of adult chronic disease morbidity.
本研究旨在评估参与“无烟宝贝与我”试验的农村吸烟孕妇的围产期结局。
在孕期收集吸烟状况及其他产前变量的数据。通过查阅161例单胎分娩(对照组79例,干预组82例)的医院记录获取结局数据。
结果显示,在调整性别和孕周后,首次产前检查时自我报告的吸烟量越多,婴儿出生体重越低(p = 0.033),母亲体重增加越少(p = 0.042),产程越短(p = 0.041)。干预组中首次产前检查尿可替宁呈阳性的女性所生婴儿的1分钟阿氏评分高于可替宁呈阴性的女性所生婴儿(p = 0.022)。吸烟者的男婴占比更高(64%对36%),而非吸烟者的女婴占比更高(59%对41%)(p = 0.006)。
孕期吸烟会影响围产期结局。假设慢性病发病源于胎儿期,孕期戒烟不仅能改善母婴健康,还可能有助于降低成人慢性病的发病率。