Ricci Lesley A, Melloni Richard H
Department of Psychology, Northeastern University, Boston, MA 02155, USA.
Behav Neurosci. 2013 Feb;127(1):130-2. doi: 10.1037/a0031482.
A Commentary published in the October 2012 issue of Behavioral Neuroscience entitled "SSRIs, Adolescents, and Aggression: Tempering Human Implications Regarding SSRI-Induced Aggression in Hamsters: Comment on Ricci and Melloni (2012)", presents an interpretation of findings from our report published in the same issue of Behavioral Neuroscience entitled "Repeated Fluoxetine Administration During Adolescence Stimulates Aggressive Behavior and Alters Serotonin and Vasopressin Neural Development in Hamsters". The commentary was informative, especially in its review of the prescribing demographics for SSRIs in youth and its review of human and animal aggression subtypes, and in several instances offered alternative explanations and interpretations of evidence cited in our report, particularly regarding putative relationships between human and animal models of aggression. In our response, we reply to comments made by the authors regarding the animal model of choice for our studies, the methodologies employed and the greater implication(s) of our published study as well as offer a disparate view of the evidence cited by the authors in their commentary as they pertain to the relevance of the models of aggression used in our study.
一篇发表于2012年10月《行为神经科学》杂志的评论文章，标题为《选择性5-羟色胺再摄取抑制剂、青少年与攻击行为：关于仓鼠中选择性5-羟色胺再摄取抑制剂诱发攻击行为的人类影响的缓和：评里奇和梅洛尼（2012年）》，对我们发表在同一期《行为神经科学》上的报告结果进行了解读，我们的报告标题为《青春期重复给予氟西汀会刺激仓鼠的攻击行为并改变其血清素和加压素神经发育》。这篇评论文章提供了丰富的信息，尤其是在对青少年使用选择性5-羟色胺再摄取抑制剂的处方统计数据进行回顾，以及对人类和动物攻击行为亚型进行回顾方面，并且在多个实例中对我们报告中引用的证据提供了不同的解释，特别是关于人类和动物攻击行为模型之间的假定关系。在我们的回应中，我们回复了作者关于我们研究中所选用的动物模型、所采用的方法以及我们已发表研究的更大意义等方面的评论，同时也对作者在评论中引用的、与我们研究中使用的攻击行为模型的相关性有关的证据提出了不同的看法。
