Department of Surgery, University Medical Center Groningen, Groningen, The Netherlands.
Colorectal Dis. 2013 May;15(5):e271-5. doi: 10.1111/codi.12167.
Reported incidence rates of colorectal anastomotic leakage (AL) vary between 2.5 and 20%. There is little information on late anastomotic leakage (LAL). The aim of this study was to determine the incidence of LAL after colorectal resection.
All patients undergoing colorectal resection with primary anastomosis between January 2004 and October 2009 at the University Medical Center Groningen were included. LAL was defined as anastomotic leakage diagnosed more than 30 days after surgery.
One hundred and forty-one patients were analysed. Indications for surgery included both benign and malignant conditions. The incidence of early anastomotic leakage (EAL) within 30 days after surgery was 13%. The LAL rate was 6%. Eighty-nine per cent of patients with EAL underwent relaparotomy compared with 44% for LAL (P = 0.02).
One-third of all anastomotic leakages were diagnosed more than 30 days after surgery. Of these, 44% underwent relaparotomy. Patients with leakage diagnosed within 30 days after surgery were more likely to undergo relaparotomy. LAL is a significant problem after colorectal surgery.
结直肠吻合口漏（AL）的报告发病率在 2.5%至 20%之间。关于晚期吻合口漏（LAL）的信息很少。本研究旨在确定结直肠切除术后 LAL 的发生率。
纳入 2004 年 1 月至 2009 年 10 月在格罗宁根大学医学中心行结直肠切除术且行一期吻合的所有患者。将术后 30 天以上诊断的吻合口漏定义为 LAL。
对 141 例患者进行了分析。手术的适应证包括良性和恶性疾病。术后 30 天内早期吻合口漏（EAL）的发生率为 13%。LAL 的发生率为 6%。EAL 患者中有 89%行再次剖腹手术，而 LAL 患者为 44%（P = 0.02）。
所有吻合口漏中有三分之一是在术后 30 天以上诊断的。其中，44%行再次剖腹手术。术后 30 天内诊断出的漏诊患者更有可能行再次剖腹手术。LAL 是结直肠手术后的一个严重问题。
