Brannan D K, Dille J C
Department of Biology, Abilene Christian University, Texas 79699.
Appl Environ Microbiol. 1990 May;56(5):1476-9. doi: 10.1128/aem.56.5.1476-1479.1990.
The dispensing closure used for containers plays an important role in protecting cosmetics from in-use microbial contamination. This hypothesis was tested by aseptically packing unpreserved shampoo and skin lotion into containers with three different closure types which provided various degrees of protection against consumer and environmental microbial insults. Shampoo was packed in containers with slit-cap (n = 25), flip-cap (n = 25), or screw-cap (n = 28) closures. Skin lotion was packed in containers with pump-top (n = 21), flip-cap (n = 18), or screw-cap (n = 21) closures. The products were then used by volunteers under actual in-use conditions for 3 (shampoo) or 2 (skin lotion) weeks. After use, the products were evaluated for microbial contamination by using standard methods for enumeration and identification. The standard screw-cap closure provided only minimal protection against microbial contamination of both the shampoo (29% contamination incidence) and the skin lotion (71%). The slit-cap closure on the shampoo container and the flip-cap closure on the skin lotion container provided slightly enhanced degrees of protection (21 and 39% contamination incidence, respectively). The greatest amount of protection (i.e., lowest contamination incidence) was provided by the flip-cap closure for the shampoo container (0%) and the pump-top closure for the skin lotion container (10%). As a result, closure type plays an important role in protecting poorly preserved products from in-use microbial contamination.
用于容器的分装瓶盖在保护化妆品免受使用过程中的微生物污染方面起着重要作用。通过将未添加防腐剂的洗发水和护肤乳液无菌包装到具有三种不同瓶盖类型的容器中来验证这一假设,这三种瓶盖类型提供了不同程度的保护,以抵御消费者和环境中的微生物侵害。洗发水被包装在带有狭缝盖(n = 25)、翻盖盖(n = 25)或螺帽盖(n = 28)的容器中。护肤乳液被包装在带有泵头盖(n = 21)、翻盖盖(n = 18)或螺帽盖(n = 21)的容器中。然后志愿者在实际使用条件下使用这些产品3周(洗发水)或2周(护肤乳液)。使用后,通过使用标准的计数和鉴定方法对产品的微生物污染情况进行评估。标准螺帽盖对洗发水(污染发生率29%)和护肤乳液(污染发生率71%)的微生物污染仅提供了最小程度的保护。洗发水容器上的狭缝盖和护肤乳液容器上的翻盖盖提供了稍高程度的保护(污染发生率分别为21%和39%)。洗发水容器的翻盖盖(0%)和护肤乳液容器的泵头盖(10%)提供了最大程度的保护(即最低的污染发生率)。因此,瓶盖类型在保护保存不佳的产品免受使用过程中的微生物污染方面起着重要作用。