Department of Surgery, Stanford University, Stanford, CA.
Department of Internal Medicine, University of Iowa, Iowa City, IA.
Am J Transplant. 2013 Apr;13(4):851-860. doi: 10.1111/ajt.12140. Epub 2013 Feb 7.
While kidney paired donation (KPD) enables the utilization of living donor kidneys from healthy and willing donors incompatible with their intended recipients, the strategy poses complex challenges that have limited its adoption in United States and Canada. A consensus conference was convened March 29-30, 2012 to address the dynamic challenges and complexities of KPD that inhibit optimal implementation. Stakeholders considered donor evaluation and care, histocompatibility testing, allocation algorithms, financing, geographic challenges and implementation strategies with the goal to safely maximize KPD at every transplant center. Best practices, knowledge gaps and research goals were identified and summarized in this document.
虽然配对供肾(KPD)可以利用与受者不相容的健康、有意愿的供者的肾脏,但该策略存在复杂的挑战,限制了其在美国和加拿大的应用。为了解决阻碍最佳实施的 KPD 的动态挑战和复杂性,于 2012 年 3 月 29 日至 30 日召开了一次共识会议。利益相关者考虑了供者评估和护理、组织相容性检测、分配算法、融资、地理挑战以及实施策略,目标是在每个移植中心安全地最大限度地提高 KPD。本文档中确定并总结了最佳实践、知识空白和研究目标。