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使用牛肺肝素避免猪肠肝素引起的过敏性休克。

Use of bovine lung heparin to obviate anaphylactic shock caused by porcine gut heparin.

作者信息

Harada A, Tatsuno K, Kikuchi T, Takahashi Y, Sai S, Murakami Y, Takada K

机构信息

Division of Cardiac Surgery, Sakakibara Heart Institute, Tokyo, Japan.

出版信息

Ann Thorac Surg. 1990 May;49(5):826-7. doi: 10.1016/0003-4975(90)90037-7.

Abstract

Intracardiac repair in a 7-year-old girl with tetralogy of Fallot was hampered because of an anaphylactic reaction with cardiopulmonary collapse caused by porcine gut heparin. This patient had an extremely rare case of hypersensitivity to porcine gut heparin but not to bovine lung heparin. Uneventful radical operation could be performed with the use of bovine lung heparin for systemic heparinization during cardiopulmonary bypass.

摘要

一名患有法洛四联症的7岁女孩,因猪肠肝素引发过敏反应导致心肺功能衰竭,心脏内修复手术受阻。该患者对猪肠肝素过敏极为罕见,但对牛肺肝素不过敏。在体外循环期间使用牛肺肝素进行全身肝素化,得以顺利进行根治性手术。

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