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腱鞘纤维瘤——一种罕见的手部肿瘤。

Fibroma of the tendon sheath - a rare hand tumor.

作者信息

Heckert Reed, Bear Jonathan, Summers Thomas, Frew Michael, Gwinn David, McKay Patricia

出版信息

Pol Przegl Chir. 2012 Dec;84(12):651-6. doi: 10.2478/v10035-012-0107-z.

Abstract

Fibroma of the tendon sheath (FTS) is a rare, benign, soft tissue lesion. Clinically, FTS presents similarly to the more common giant cell tumor of the tendon sheath. It is distinguished histologically by the lack of giant cells, foamy histiocytes and synovial cells. We presented a case of FTS involving the common tendon sheath surrounding the flexor tendons leading to the third metacarpal. A 63-year-old man presented with a 3-month history of a painless mass in his right palm that had recently tripled in size. Examination demonstrated a 5x4 cm firm, nodular, superficial mass that was adherent to the overlying skin. Radiographs of the hand revealed a soft tissue mass without bony abnormality. Ultrasound demonstrated a solid, heterogeneous and hypoechoic mass and computed tomography demonstrated that the mass centered predominantly at the mid and distal portions of the third metacarpal. The patient underwent excisional biopsy of the lesion and a palmar, longitudinal incision was made from the wrist to the third metacarpal. Submitted histologic sections revealed a well-circumscribed lesion closely resembling hyalinized collagen. Neither vascular proliferations, necrosis, nor mitoses were observed. Similarly, multinucleated giant cells, pigment-laden macrophages, and inflammatory cells were also not identified. A diagnosis of FTS was rendered. We provided an additional rare case to the literature of a FTS and highlight the need to consider this entity in the differential diagnosis for any soft tissue lesion in the hand. Three months post surgery the patient demonstrated full range of motion of the hand.

摘要

腱鞘纤维瘤(FTS)是一种罕见的良性软组织病变。临床上,FTS的表现与更常见的腱鞘巨细胞瘤相似。在组织学上,它的特征是缺乏巨细胞、泡沫状组织细胞和滑膜细胞。我们报告了一例FTS累及通向第三掌骨的屈肌腱周围的共同腱鞘。一名63岁男性患者,右手掌出现无痛性肿块3个月,近期肿块大小增至原来的三倍。检查发现一个5×4厘米的坚实、结节状、浅表肿块,与上方皮肤粘连。手部X线片显示软组织肿块,无骨质异常。超声显示为实性、不均匀且低回声肿块,计算机断层扫描显示肿块主要位于第三掌骨的中、远端。患者接受了病变的切除活检,从腕部至第三掌骨做了一个掌侧纵向切口。送检的组织学切片显示一个边界清楚的病变,与透明变性的胶原非常相似。未观察到血管增生、坏死或有丝分裂。同样,也未发现多核巨细胞、含色素巨噬细胞和炎症细胞。作出了FTS的诊断。我们为FTS的文献增添了另一例罕见病例,并强调在手部任何软组织病变的鉴别诊断中都需要考虑这一疾病。术后三个月,患者手部活动范围完全正常。

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