Farmer R G
Postgrad Med. 1975 Jan;57(1):129-36. doi: 10.1080/00325481.1975.11713949.
Crohn's disease is a perplexing disease with a high rate of morbidity and complications. The incidence appears to be increasing. The cause is unknown, and response to medical therapy has been disappointing. Diagnosis may be very difficult and often is delayed. A high proportion of patients eventually require surgery, and an appreciable percentage will have recurrence of disease afterward. The prognosis in terms of responsiveness to medical therapy is believed to be poorer than the prognosis of ulcerative colitis. A national cooperative study to assess drug therapy prospectively is under way.
克罗恩病是一种复杂的疾病，发病率和并发症发生率都很高。其发病率似乎在上升。病因不明，药物治疗的效果一直令人失望。诊断可能非常困难，而且常常延误。很大一部分患者最终需要手术治疗，并且有相当比例的患者术后疾病会复发。据信，就对药物治疗的反应而言，其预后比溃疡性结肠炎更差。一项评估药物治疗前景的全国性合作研究正在进行中。
