Department of Pharmacy Practice, University of Connecticut School of Pharmacy, Storrs, Connecticut 06030, USA.
Pharmacotherapy. 2013 Jun;33(6):e115-42. doi: 10.1002/phar.1252. Epub 2013 Feb 11.
Ischemic stroke is a prevalent disease with a large burden on the health system. It is essential for practitioners caring for patients who have experienced an ischemic stroke to be familiar with the literature supporting both acute management as well as secondary preventive strategies. Due to the large amount of literature available on this topic, this bibliography (the second of a two-part series) aims to provide a comprehensive resource for medical practitioners charged with caring for this population. Acute management strategies involve controlling patients' blood pressure and administering thrombolysis (either pharmacologic or mechanical) to improve blood flow and preserve neurologic function. Various neuroprevention strategies have also been investigated. Secondary prevention strategies, similar to primary prevention, focus on modulation of various risk factors including antiplatelet treatments and control of blood pressure, and lipid levels, amongst others.
缺血性脑卒中是一种常见疾病，给医疗系统带来了沉重负担。对于照顾缺血性脑卒中患者的医生来说，熟悉支持急性治疗和二级预防策略的文献至关重要。由于这个主题有大量的文献，这个文献目录（两部分系列中的第二部分）旨在为负责照顾这一人群的医疗从业者提供一个全面的资源。急性治疗策略包括控制患者的血压和给予溶栓治疗（无论是药物还是机械）以改善血流和保护神经功能。还研究了各种神经保护策略。二级预防策略与一级预防相似，侧重于调节各种危险因素，包括抗血小板治疗以及血压和血脂水平的控制等。
