Department of Medical Physics, Cross Cancer Institute, Edmonton, Alberta, Canada.
NMR Biomed. 2013 May;26(5):533-41. doi: 10.1002/nbm.2890. Epub 2013 Feb 11.
Proton-decoupled, (13) C nuclear MRS experiments require a RF coil that operates at the Larmor frequencies of both (13) C and (1) H. In this work, we designed, built and tested a single-unit, dual-tuned coil based on a half-birdcage open coil design. It was constructed as a low-pass network with a resonant trap in series with each leg. Traps are tuned in alternate legs such that the two resonant modes arise from currents on alternate legs. The coil performance was compared with that of a dual-tuned coil consisting of two proton surface coils operating in quadrature and a single surface coil for (13) C transmission and reception. The half-birdcage coil was shown to produce a more homogeneous RF field at each frequency and was more sensitive to a (13) C signal arising from regions further from the coil surface. The applicability of the coil in vivo was demonstrated by acquiring a proton decoupled, natural abundance (13) C glycogen signal from the calf of a normal volunteer.
质子去耦，（13）C 核磁共振波谱实验需要一个在（13）C 和（1）H 的拉莫尔频率下工作的射频线圈。在这项工作中，我们设计、构建并测试了一个基于半鸟笼开环线圈设计的单单元双调谐线圈。它被构建为一个低通网络，每个支腿上串联一个谐振陷波。陷波在交替的支腿上进行调谐，使得两个谐振模式来自于交替支腿上的电流。将线圈性能与由两个质子表面线圈组成的双调谐线圈以及用于（13）C 发射和接收的单个表面线圈进行了比较。结果表明，半鸟笼线圈在每个频率下产生更均匀的射频场，并且对来自线圈表面更远的区域的（13）C 信号更敏感。通过从正常志愿者的小腿获取质子去耦、自然丰度（13）C 糖原信号，证明了该线圈在体内的适用性。
