Göbölös L, Miskolczi S, Pousios D, Tsang G M, Livesey S A, Barlow C W, Kaarne M, Shambrook J, Lipnevicius A, Ohri S K
Department Cardiothoracic Surgery, Southampton General Hospital, Southampton University Hospital Trust, Southampton, UK.
Perfusion. 2013 Jul;28(4):286-90. doi: 10.1177/0267659113476329. Epub 2013 Feb 11.
An aorto-oesophageal fistula is a rare clinical entity, leading to life-threatening gastrointestinal bleeding. Thoracic aortic aneurysms are the most common cause of aorto-oesophageal fistulae; further causes involve foreign body ingestion, trauma (in most cases iatrogenic), carcinoma or, very rarely, aortitis tuberculotica.
Due to its rarity, there are no large multicentre studies present to evaluate the efficacy of different therapeutic management options. Since it is associated with significant morbidity and mortality, we give a short summary of various treatment approaches performed in our clinical practice in the past three years. The most straightforward therapeutic option may be an endovascular aortic repair and subtotal oesophageal resection followed by gastro-oesophageal reconstruction, but other alternative treatment possibilities are also present, although with probable higher morbidity.
Eliminating the source of bleeding as an emergency, resecting the oesophagus urgently to prevent sepsis and reconstructing the gastrointestinal continuity as an elective case after having the inflammatory processes settled seems to justify the endovascular aortic repair and subtotal oesophageal resection, followed by a gastro-oesophageal reconstruction, as an effective surgical approach.
主动脉-食管瘘是一种罕见的临床病症,可导致危及生命的胃肠道出血。胸主动脉瘤是主动脉-食管瘘最常见的病因;其他病因包括异物吞食、创伤(多数情况下为医源性)、癌症,或极为罕见的结核性主动脉炎。
鉴于其罕见性,目前尚无大型多中心研究来评估不同治疗管理方案的疗效。由于其与显著的发病率和死亡率相关,我们简要总结了过去三年我们临床实践中采用的各种治疗方法。最直接的治疗选择可能是血管腔内主动脉修复术和食管次全切除术,随后进行胃食管重建,但也存在其他替代治疗可能性,尽管发病率可能更高。
作为紧急情况消除出血源、紧急切除食管以预防脓毒症,并在炎症过程消退后作为择期病例重建胃肠道连续性,这似乎证明血管腔内主动脉修复术和食管次全切除术,随后进行胃食管重建是一种有效的手术方法。