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[聚乙二醇化干扰素与标准干扰素相比的血液学安全性]

[Pegylated intereferon hematological safety in comparison with standard].

作者信息

Fazylov V Kh, Manapova É R, Tkacheva S V, Sozinova Iu M

出版信息

Eksp Klin Gastroenterol. 2012(6):96-9.

PMID:23402198
Abstract

Comparative analysis of adverse hematologic effects in 135 patients with with chronic hepatits C on combined antiviral therapy of pegylated and "short lived" forms of alpha-interferon in combination with ribavirin was investigated. As a result of the comparison, the response to antiviral therapy in patients with chronic hepatitis C treated with daily administration of simple interferon-alpha in hematologic data is similar in patients undergoing treatment with pegylated drugs.

摘要

对135例慢性丙型肝炎患者采用聚乙二醇化和“短效”形式的α-干扰素联合利巴韦林进行抗病毒联合治疗时的不良血液学效应进行了对比分析。对比结果显示,在血液学数据方面,每日给予普通α-干扰素治疗的慢性丙型肝炎患者对抗病毒治疗的反应与接受聚乙二醇化药物治疗的患者相似。

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