Joint Ludwig Austin Oncology Unit, Melbourne, Victoria, Australia.
Intern Med J. 2013 Feb;43(2):211-4. doi: 10.1111/imj.12018.
Non-bacterial thrombotic endocarditis (NBTE), also known as marantic endocarditis, has been reported to occur in 0.3-9.3% of the adult population at autopsy. NBTE associated with malignancy is an underrecognised cause of thromboembolic disorders. The clinical spectrum encountered and investigation results can be non-specific, often mimicking other acute conditions such as infective endocarditis. We describe the case of a 34-year-old woman with non-localising and multifocal neurological symptoms, who was subsequently diagnosed with NBTE secondary to a resectable primary lung adenocarcinoma.
非细菌性血栓性心内膜炎(NBTE),也称为风湿性心内膜炎,尸检报告显示成年人中发病率为 0.3-9.3%。NBTE 合并恶性肿瘤是一种未被充分认识的血栓栓塞性疾病的病因。其临床表现和检查结果可能无特异性,常类似于其他急性疾病,如感染性心内膜炎。我们描述了一例 34 岁女性,表现为非定位性和多灶性神经症状,随后诊断为可切除的原发性肺腺癌继发的 NBTE。