Department of Physical Medicine and Rehabilitation, Wexner Medical Center at The Ohio State University, Columbus, OH 43210, USA.
Arch Phys Med Rehabil. 2013 Jun;94(6):1199-201. doi: 10.1016/j.apmr.2013.01.023. Epub 2013 Feb 10.
Growing evidence indicates that multiple types of brain injury, including traumatic brain injury, are dynamic conditions that continue to change years after onset. For a subset of individuals who incur these injuries, decline occurs over time and is likely due to progressive neurodegenerative processes, comorbid conditions, aging, behavioral choices, and/or psychosocial factors. Deterioration, whether directly or indirectly associated with the original brain injury, necessitates a clinical approach as a chronic health condition, including identification of risk and protective factors, protocols for early identification, evidence-based preventive and ameliorative treatment, and training in self-management. We propose that the acknowledgment of chronic brain injury will facilitate the research necessary to provide a disease management approach.
越来越多的证据表明,多种类型的脑损伤,包括创伤性脑损伤,都是持续变化的状况,即使在发病多年后仍在继续变化。对于发生这些损伤的一部分人来说,随着时间的推移会出现衰退,这很可能是由于进行性神经退行性过程、合并症、衰老、行为选择和/或社会心理因素造成的。无论是直接还是间接与最初的脑损伤相关的恶化,都需要将其作为一种慢性健康状况来采取临床处理方法,包括确定风险和保护因素、早期识别的方案、基于证据的预防和改善治疗以及自我管理的培训。我们认为,承认慢性脑损伤将有助于开展必要的研究,从而提供一种疾病管理方法。