社区获得性艰难梭菌感染：它有多真实？
Community-associated Clostridium difficile infection: how real is it?
机构信息
Division of Healthcare Quality Promotion, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS A-24, Atlanta, GA 30333, USA.
出版信息
Anaerobe. 2013 Dec;24:121-3. doi: 10.1016/j.anaerobe.2013.01.006. Epub 2013 Feb 8.
Abstract
Community-associated Clostridium difficile infection (CA-CDI) represents 32% of all CDI cases based on U.S. population-based data. The current epidemic strain, NAP1, is the most prevalent strain causing these infections. Although complications, recurrence and death are uncommon, one-fourth of the CA-CDI patients are hospitalized within 7 days after the diagnosis.
摘要
基于美国人口数据，社区获得性艰难梭菌感染（CA-CDI）占所有 CDI 病例的 32%。目前流行的菌株NAP1 是导致这些感染的最常见菌株。尽管并发症、复发和死亡并不常见，但四分之一的 CA-CDI 患者在诊断后 7 天内住院。
相似文献
1
Community-associated Clostridium difficile infection: how real is it?社区获得性艰难梭菌感染：它有多真实？
Anaerobe. 2013 Dec;24:121-3. doi: 10.1016/j.anaerobe.2013.01.006. Epub 2013 Feb 8.
2
Outcomes in community-acquired Clostridium difficile infection.社区获得性艰难梭菌感染的结局。
Aliment Pharmacol Ther. 2012 Mar;35(5):613-8. doi: 10.1111/j.1365-2036.2011.04984.x. Epub 2012 Jan 10.
3
Clostridium difficile infection in children hospitalized due to diarrhea.儿童因腹泻住院时的艰难梭菌感染。
Eur J Clin Microbiol Infect Dis. 2014 Feb;33(2):201-9. doi: 10.1007/s10096-013-1946-1. Epub 2013 Nov 10.
4
Burden of community-associated Clostridioides difficile infection in southeastern United States: a population-based study.美国东南部社区相关艰难梭菌感染的负担：一项基于人群的研究。
Infection. 2020 Feb;48(1):129-132. doi: 10.1007/s15010-019-01368-5. Epub 2019 Nov 1.
5
Epidemiology of community-associated Clostridium difficile infection, 2009 through 2011.社区获得性艰难梭菌感染的流行病学，2009 年至 2011 年。
JAMA Intern Med. 2013 Jul 22;173(14):1359-67. doi: 10.1001/jamainternmed.2013.7056.
6
The epidemiology of Clostridium difficile infection in children: a population-based study.儿童艰难梭菌感染的流行病学：一项基于人群的研究。
Clin Infect Dis. 2013 May;56(10):1401-6. doi: 10.1093/cid/cit075. Epub 2013 Feb 13.
7
Epidemiological and genomic characterization of community-acquired Clostridium difficile infections.社区获得性艰难梭菌感染的流行病学和基因组特征。
BMC Infect Dis. 2018 Aug 31;18(1):443. doi: 10.1186/s12879-018-3337-9.
8
Population-based surveillance of Clostridium difficile infection in Manitoba, Canada, by using interim surveillance definitions.加拿大曼尼托巴省采用临时监测定义对艰难梭菌感染进行基于人群的监测。
Infect Control Hosp Epidemiol. 2009 Oct;30(10):945-51. doi: 10.1086/605719.
9
Characterization of Adult and Pediatric Healthcare-Associated and Community-Associated Clostridioides difficile Infections, Canada, 2015-2022.2015 - 2022年加拿大成人及儿童医疗保健相关和社区相关艰难梭菌感染的特征
Emerg Infect Dis. 2025 Jun;31(6):1109-1120. doi: 10.3201/eid3106.250182.
10
Regional and seasonal variation in Clostridium difficile infections among hospitalized patients in the United States, 2001-2010.2001年至2010年美国住院患者艰难梭菌感染的地区和季节差异
Am J Infect Control. 2015 May 1;43(5):435-40. doi: 10.1016/j.ajic.2014.11.018.
引用本文的文献
1
infection after extracorporeal membrane oxygenation support for acute myocardial infarction: a case report.体外膜肺氧合支持急性心肌梗死后感染：一例报告
Front Med (Lausanne). 2023 Dec 22;10:1333209. doi: 10.3389/fmed.2023.1333209. eCollection 2023.
2
Bezlotoxumab in Patients with a Primary Infection: A Literature Review.贝佐妥昔单抗用于原发性感染患者：文献综述
Antibiotics (Basel). 2022 Oct 28;11(11):1495. doi: 10.3390/antibiotics11111495.
3
Fidaxomicin for the Treatment of Infection in Adult Patients: An Update on Results from Randomized Controlled Trials.非达霉素用于治疗成年患者感染：随机对照试验结果的最新进展
Antibiotics (Basel). 2022 Oct 6;11(10):1365. doi: 10.3390/antibiotics11101365.
4
Clostridioides difficile infection (CDI) during the COVID-19 pandemic.艰难梭菌感染（CDI）在 COVID-19 大流行期间。
Anaerobe. 2022 Apr;74:102518. doi: 10.1016/j.anaerobe.2022.102518. Epub 2022 Jan 19.
5
Association of Household Exposure to Primary Clostridioides difficile Infection With Secondary Infection in Family Members.家庭中主要艰难梭菌感染的暴露与家庭成员中二次感染的关联。
JAMA Netw Open. 2020 Jun 1;3(6):e208925. doi: 10.1001/jamanetworkopen.2020.8925.
6
colitis and zoonotic origins-a narrative review.结肠炎与动物源性起源——一篇叙述性综述
Gastroenterol Rep (Oxf). 2018 Aug;6(3):157-166. doi: 10.1093/gastro/goy016. Epub 2018 Jun 28.
7
Community Environmental Contamination of Toxigenic .产毒的社区环境污染
Open Forum Infect Dis. 2017 Feb 10;4(1):ofx018. doi: 10.1093/ofid/ofx018. eCollection 2017 Winter.
8
Epidemiology and Risk Factors for Community-Associated Clostridium difficile Infection: A Narrative Review.社区相关性艰难梭菌感染的流行病学和危险因素：一篇叙述性综述。
Infect Dis Ther. 2016 Sep;5(3):231-51. doi: 10.1007/s40121-016-0117-y. Epub 2016 Jul 1.
9
Clostridium difficile infection in a French university hospital: Eight years of prospective surveillance study.法国一家大学医院的艰难梭菌感染：八年的前瞻性监测研究
Medicine (Baltimore). 2016 Jun;95(23):e3874. doi: 10.1097/MD.0000000000003874.
10
Predominance and high antibiotic resistance of the emerging Clostridium difficile genotypes NAPCR1 and NAP9 in a Costa Rican hospital over a 2-year period without outbreaks.在哥斯达黎加一家医院为期两年且无疫情爆发的期间，新出现的艰难梭菌基因型NAPCR1和NAP9占主导地位且具有高抗生素耐药性。
Emerg Microbes Infect. 2016 May 11;5(5):e42. doi: 10.1038/emi.2016.38.
本文引用的文献
1
Development of a consensus method for culture of Clostridium difficile from meat and its use in a survey of U.S. retail meats.开发一种从肉类中培养艰难梭菌的共识方法及其在美国零售肉类调查中的应用。
Food Microbiol. 2012 Dec;32(2):448-51. doi: 10.1016/j.fm.2012.08.005. Epub 2012 Aug 21.
2
Predictors of first recurrence of Clostridium difficile infection: implications for initial management.艰难梭菌感染首次复发的预测因素：对初始治疗的影响。
Clin Infect Dis. 2012 Aug;55 Suppl 2(Suppl 2):S77-87. doi: 10.1093/cid/cis356.
3
Community-associated Clostridium difficile infections, Monroe County, New York, USA.美国纽约州门罗县社区相关艰难梭菌感染。
Emerg Infect Dis. 2012 Mar;18(3):392-400. doi: 10.3201/eid1803.102023.
4
Risk of secondary cases of Clostridium difficile infection among household contacts of index cases.家庭接触者中难辨梭状芽孢杆菌感染的二次发病风险。
J Infect. 2012 Apr;64(4):387-90. doi: 10.1016/j.jinf.2011.12.011. Epub 2011 Dec 26.
5
Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics.接触抗生素后艰难梭菌感染风险增加的时间间隔。
J Antimicrob Chemother. 2012 Mar;67(3):742-8. doi: 10.1093/jac/dkr508. Epub 2011 Dec 6.
6
Association between proton pump inhibitor therapy and Clostridium difficile infection in a meta-analysis.质子泵抑制剂治疗与艰难梭菌感染的荟萃分析。
Clin Gastroenterol Hepatol. 2012 Mar;10(3):225-33. doi: 10.1016/j.cgh.2011.09.030. Epub 2011 Oct 20.
7
Clostridium difficile in retail meat and processing plants in Texas.德克萨斯州零售肉类及加工厂中的艰难梭菌
J Vet Diagn Invest. 2011 Jul;23(4):807-11. doi: 10.1177/1040638711407893.
8
Diagnostic accuracy of real-time polymerase chain reaction in detection of Clostridium difficile in the stool samples of patients with suspected Clostridium difficile Infection: a meta-analysis.实时聚合酶链反应检测疑似艰难梭菌感染患者粪便样本中艰难梭菌的诊断准确性：一项荟萃分析。
Clin Infect Dis. 2011 Oct;53(7):e81-90. doi: 10.1093/cid/cir505.
9
Comparison of the burdens of hospital-onset, healthcare facility-associated Clostridium difficile Infection and of healthcare-associated infection due to methicillin-resistant Staphylococcus aureus in community hospitals.比较社区医院中医院获得性艰难梭菌感染和耐甲氧西林金黄色葡萄球菌所致医源性感染的负担。
Infect Control Hosp Epidemiol. 2011 Apr;32(4):387-90. doi: 10.1086/659156.
10
Risk factors for and estimated incidence of community-associated Clostridium difficile infection, North Carolina, USA.美国北卡罗来纳州社区相关艰难梭菌感染的危险因素和估计发病率。
Emerg Infect Dis. 2010 Feb;16(2):197-204. doi: 10.3201/eid1602.090953.
Zotero 插件