Okade Durga Rajaram, James Leena, Shetty Akshay, Reddy Sudhakara
Department of Oral Medicine and Radiology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.
J Contemp Dent Pract. 2012 Nov 1;13(6):930-3. doi: 10.5005/jp-journals-10024-1256.
To understand the aggressiveness of lesions in immunocompromised patients. Central giant cell granuloma (CGCG) is a non-neoplastic intraosseous lesion, anterior to the molars and more commonly in the mandible. It is an uncommon lesion accounting for less than 7% of all benign jaw lesions found predominantly in children and young adults with a female predilection of about 2:1 ratio.
A 22-year-old male patient came to the department with a growth in the anterior part of the maxilla with pain, rapid pace of growth and which recurred after initial excision as told to us in the case history.
A diagnosis of CGCG of aggressive nature should be kept in mind, in a young immunocompromised patient.
A recurrent lesion, with rapid pace of growth, associated with pain, a positive immunodeficient status, lesion in the anterior maxilla in a male patient, we can think of an aggressive CGCG.
了解免疫功能低下患者病变的侵袭性。中央巨细胞肉芽肿（CGCG）是一种非肿瘤性骨内病变，位于磨牙前方，更常见于下颌骨。它是一种罕见病变，占所有良性颌骨病变的比例不到7%，主要见于儿童和年轻人，女性患病率约为2:1。
一名22岁男性患者因上颌前部肿物前来就诊，伴有疼痛、生长迅速，且根据病史所述，初次切除后复发。
对于年轻的免疫功能低下患者，应考虑诊断为侵袭性CGCG。
对于复发性病变、生长迅速、伴有疼痛、免疫缺陷状态阳性、男性患者上颌前部病变，我们可以考虑为侵袭性CGCG。
