Patel Devaki, Minhas Gursharan, Johnson Paul
a Maxillofacial Department , Royal Surrey County Hospital Foundation Trust , Guildford, Surrey , UK.
b Orthodontic Department , Royal Surrey County Hospital Foundation Trust , Guildford, Surrey , UK.
J Orthod. 2016 Dec;43(4):306-313. doi: 10.1080/14653125.2016.1226566. Epub 2016 Sep 22.
Central giant cell granuloma (CGCG) is an uncommon benign intraosseous lesion of the jaw, found predominantly in children and young adults below 30 years of age. The purpose of this article was to present a summary of the current literature and a case report of an 11-year-old boy diagnosed with an aggressive CGCG involving the anterior maxilla that was removed in 2004 and subsequently recurred almost 3 years later in 2006. The presenting features of the patient and the effect of combined surgical and orthodontic treatment for this condition are discussed. This case shows how the dentition was successfully maintained with conservative surgery and orthodontic treatment in spite of the extensive destruction of the supporting bone, and the importance of long-term follow-up. The report also reminds orthodontic practitioners that rare pathological conditions can occur in their child patient groups.
中央巨细胞肉芽肿（CGCG）是一种罕见的颌骨良性骨内病变，主要见于30岁以下的儿童和年轻人。本文的目的是总结当前文献，并报告一例11岁男孩的病例，该男孩于2004年被诊断为侵袭性CGCG，累及上颌前部，随后在2006年近3年后复发。讨论了该患者的临床表现以及联合手术和正畸治疗对这种疾病的效果。该病例表明，尽管支持骨受到广泛破坏，但通过保守手术和正畸治疗仍成功维持了牙列，以及长期随访的重要性。该报告还提醒正畸从业者，在他们的儿童患者群体中可能会出现罕见的病理状况。
