Department of Gastroenterology, Adana Numune Training and Research Hospital, Adana, Turkey.
Obes Surg. 2013 Jul;23(7):892-6. doi: 10.1007/s11695-013-0876-4.
Most of the weight loss with the BioEnterics intragastric balloon (BIB) has occurred during the first 3-4 months. This study aimed to evaluate the effect of initial weight loss on long-term weight maintenance.
From 2008 to 2011, 50 patients who had mean body mass index (BMI) of 44.7 ± 12.4 kg/m(2) underwent BIB therapy for 6 months. All patients were given a diet of 1,100 kcal/day. Weight loss parameters [absolute weight loss, BMI loss, percentage of body weight loss (BWL%), and percentage of excess BMI loss] were recorded at the baseline, 1 month, 6 months (time of BIB removal), 12 months, and 18 months from the baseline. Successful weight loss was defined as ≥ 10 % weight loss after 6, 12, and 18 months.
Twenty-seven patients (54 %) achieved a percentage of BWL ≥ 10 at the time of removal. Eighteen (36 %) and 12 (24 %) patients were able to maintain weight loss of 10 % at 12 and 18 months. Percentage of BWL after 1 month was positively correlated with BWL% after 6, 12, and 18 months (r = 0.77, 0.65, and 0.62, p < 0.001, respectively). Twenty-four patients who lost 5 % of the BWL after 1 month of treatment succeeded in maintaining a lasting percentage of BWL ≥ 10 after the BIB removal: more precisely, this cutoff point was achieved in 96 % at the time of removal and in 71 %, 50 % at 12 months, and 18 months of follow-up.
Five percent BWL after 1 month of treatment may be a predictor for long-term weight maintenance.
大多数减重是在使用胃内球囊（BIB）的前 3-4 个月发生的。本研究旨在评估初始减重对长期体重维持的影响。
2008 年至 2011 年，50 名平均 BMI（体重指数）为 44.7 ± 12.4 kg/m²的患者接受了 6 个月的 BIB 治疗。所有患者给予 1100 千卡/天的饮食。在基线、1 个月、6 个月（BIB 取出时）、12 个月和 18 个月记录体重减轻参数[绝对体重减轻、BMI 减轻、体重减轻百分比（BWL%）和多余 BMI 减轻百分比]。成功的体重减轻定义为 6、12 和 18 个月后体重减轻≥10%。
27 名患者（54%）在 BIB 取出时达到 BWL%≥10。18 名（36%）和 12 名（24%）患者能够在 12 个月和 18 个月维持 10%的体重减轻。1 个月后的 BWL%与 6、12 和 18 个月后的 BWL%呈正相关（r=0.77、0.65 和 0.62，p<0.001）。24 名患者在治疗后 1 个月体重减轻 5%，成功地维持了 BIB 取出后 BWL%≥10的持续比例：更确切地说，BIB 取出时这一截止点的达成率为 96%，12 个月和 18 个月随访时分别为 71%和 50%。
治疗后 1 个月的 BWL 减少 5%可能是长期体重维持的预测因素。
