Ogata K, Tanabe Y, Iwakiri K, Ito T, Yamada T, Dan K, Nomura T
Third Department of Internal Medicine, Nippon Medical School, Tokyo, Japan.
Cancer. 1990 Jun 15;65(12):2793-5. doi: 10.1002/1097-0142(19900615)65:12<2793::aid-cncr2820651231>3.0.co;2-s.
Two patients with acute leukemia in whom disseminated Trichosporon beigelii infection developed are reported. The T. beigelii infection developed in the first patient while he was receiving 5-fluorocytosine. He was treated with amphotericin B in addition to 5-fluorocytosine. Despite the continued antifungal therapy, multiple organs were invaded by the organisms at autopsy. The second patient was treated with miconazole and norfloxacin. Although this combination antifungal therapy seemed to be effective, this patient required splenectomy for cure of the infection.
报告了两名发生播散性白吉利毛孢子菌感染的急性白血病患者。第一名患者在接受5-氟胞嘧啶治疗时发生了白吉利毛孢子菌感染。除5-氟胞嘧啶外，他还接受了两性霉素B治疗。尽管持续进行抗真菌治疗，但尸检时多个器官仍被该菌侵袭。第二名患者接受了咪康唑和诺氟沙星治疗。尽管这种联合抗真菌治疗似乎有效，但该患者需要进行脾切除术以治愈感染。
