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Review of shell models for contrast agent microbubbles.对比剂微泡的壳模型综述。
IEEE Trans Ultrason Ferroelectr Freq Control. 2011 May;58(5):981-93. doi: 10.1109/TUFFC.2011.1899.
4
Ultrasonic characterization of ultrasound contrast agents.超声造影剂的超声特性分析。
Med Biol Eng Comput. 2009 Aug;47(8):861-73. doi: 10.1007/s11517-009-0497-1. Epub 2009 May 26.
5
Clinical uses of microbubbles in diagnosis and treatment.微泡在诊断和治疗中的临床应用。
Med Biol Eng Comput. 2009 Aug;47(8):813-26. doi: 10.1007/s11517-009-0434-3. Epub 2009 Feb 10.
6
Ultrasonic excitation of a bubble inside a deformable tube: implications for ultrasonically induced hemorrhage.可变形管内气泡的超声激发：对超声诱导出血的影响。
J Acoust Soc Am. 2008 Oct;124(4):2374-84. doi: 10.1121/1.2967488.
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Ultrasound-driven microbubble oscillation and translation within small phantom vessels.超声驱动微泡在小型仿体血管内的振荡与平移。
Ultrasound Med Biol. 2007 Dec;33(12):1978-87. doi: 10.1016/j.ultrasmedbio.2007.06.007. Epub 2007 Sep 27.
8
Microbubble contrast agents: targeted ultrasound imaging and ultrasound-assisted drug-delivery applications.微泡造影剂：靶向超声成像及超声辅助药物递送应用
Invest Radiol. 2006 Mar;41(3):354-62. doi: 10.1097/01.rli.0000199292.88189.0f.
9
Forced linear oscillations of microbubbles in blood capillaries.血液毛细血管中微泡的强迫线性振荡。
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模拟血管内微泡超声处理的动力学

Dynamics of micro-bubble sonication inside a phantom vessel.

作者信息

Qamar Adnan, Samtaney Ravi, Bull Joseph L

机构信息

King Abdullah University of Science and Technology (KAUST), Division of Physical Sciences and Engineering, Thuwal, Kingdom of Saudi Arabia.

出版信息

Appl Phys Lett. 2013 Jan 7;102(1):13702. doi: 10.1063/1.4773909. Epub 2013 Jan 10.

DOI:10.1063/1.4773909
PMID:23405034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3555874/
Abstract

A model for sonicated micro-bubble oscillations inside a phantom vessel is proposed. The model is not a variant of conventional Rayleigh-Plesset equation and is obtained from reduced Navier-Stokes equations. The model relates the micro-bubble oscillation dynamics with geometric and acoustic parameters in a consistent manner. It predicts micro-bubble oscillation dynamics as well as micro-bubble fragmentation when compared to the experimental data. For large micro-bubble radius to vessel diameter ratios, predictions are damped, suggesting breakdown of inherent modeling assumptions for these cases. Micro-bubble response with acoustic parameters is consistent with experiments and provides physical insight to the micro-bubble oscillation dynamics.

摘要

提出了一种用于模拟仿体血管内超声微泡振荡的模型。该模型并非传统瑞利 - 普莱斯方程的变体，而是由简化的纳维 - 斯托克斯方程推导得出。该模型以一种连贯的方式将微泡振荡动力学与几何参数和声学参数联系起来。与实验数据相比，它能够预测微泡振荡动力学以及微泡破碎情况。对于较大的微泡半径与血管直径之比，预测结果出现衰减，这表明在这些情况下固有建模假设失效。微泡对声学参数的响应与实验结果一致，并为微泡振荡动力学提供了物理见解。