临床评估向当前非使用者适配环曲面软性隐形眼镜。

Clinical evaluation of fitting toric soft contact lenses to current non-users.

机构信息

Johnson & Johnson Vision Care, Wokingham, UK.

出版信息

Ophthalmic Physiol Opt. 2013 Mar;33(2):94-103. doi: 10.1111/opo.12028.

DOI:10.1111/opo.12028

PMID:23406489

Abstract

PURPOSE

To evaluate the ease with which astigmats from three groups of current non-wearers of toric contact lenses can be fitted with current toric soft lenses, and to determine toric lens-wearing success.

METHODS

This was a 1-month, randomized, bilateral, open-label, daily wear study involving 200 subjects and 16 investigational sites in the UK. Three groups of astigmatic subjects aged from 16 to 60 and with a mean age of 36 years (67 spherical soft contact lens users, SW; 72 contact lens drop-outs, DO; and 61 neophytes, Neo) were fitted with one of two toric soft lens types: a daily disposable toric soft lens (1 Day Acuvue Moist for Astigmatism, Johnson & Johnson Vision Care) or a 2-weekly replacement, re-usable toric soft lens (Acuvue Oasys for Astigmatism, Johnson & Johnson Vision Care). Subjects were evaluated after 1 month of wear and success rates calculated according to pre-set criteria for acceptable fit, orientation stability, visual acuity, quality of vision, and overall comfort.

RESULTS

Eighty-eight percent of lenses were fitted at the first attempt. Of 198 subjects dispensed with lenses, 182 (92%) completed the study. When analysed by subject group, the success rates according to the pre-set criteria were 80% (53/66), 74% (52/70), and 70% (39/56) for the SW, DO and Neo groups respectively. Comfort was the most common reason for failure with all three groups; however, visual problems were more common in the DO and Neo groups (13% vs 6%). VA with the study lenses was significantly better in the SW group compared to their habitual lenses. For the DO and Neo groups combined (i.e. spectacle wearers), visual acuity was comparable to their habitual spectacles.

CONCLUSIONS

A high proportion of astigmats who are not using toric soft contact lenses can be fitted with current lenses. Previous contact lens drop-outs and neophyte wearers achieve visual acuity comparable to spectacles when fitted with toric soft lenses. Spherical contact lens wearing astigmats achieve superior visual acuity when refitted with toric soft lenses. These findings suggest that many astigmats who are not currently using toric soft contact lenses could do so successfully.

摘要

目的

评估三组当前非散光软性隐形眼镜佩戴者的散光患者使用当前散光软性隐形眼镜的舒适度，并确定散光隐形眼镜佩戴的成功率。

方法

这是一项为期 1 个月的、随机的、双侧、开放标签、每日佩戴研究，涉及英国的 200 名受试者和 16 个研究点。年龄在 16 至 60 岁之间，平均年龄为 36 岁的三组散光患者（67 名球面软性隐形眼镜使用者，SW；72 名隐形眼镜脱落者，DO；61 名新手，Neo）被试戴两种类型的散光软性隐形眼镜之一：日抛散光软性隐形眼镜（1 天 Acuvue Moist for Astigmatism，Johnson & Johnson Vision Care）或两周更换、可重复使用的散光软性隐形眼镜（Acuvue Oasys for Astigmatism，Johnson & Johnson Vision Care）。受试者在佩戴 1 个月后进行评估，并根据可接受的适配性、稳定性、视力、视觉质量和整体舒适度的预设标准计算成功率。

结果

88%的镜片在第一次尝试时就适配成功。在配给镜片的 198 名受试者中，有 182 名（92%）完成了研究。按受试者组分析，根据预设标准的成功率分别为 SW 组 80%（53/66）、DO 组 74%（52/70）和 Neo 组 70%（39/56）。舒适度是所有三组最常见的失败原因；然而，视觉问题在 DO 和 Neo 组更为常见（13%比 6%）。与习惯性镜片相比，SW 组佩戴研究镜片的视力明显更好。对于 DO 和 Neo 组（即佩戴眼镜者）的视力而言，其视力与习惯性眼镜相当。