Michaud Langis, Bennett Edward S, Woo Stephanie L, Reeder Renee, Morgan Bruce W, Dinardo Amy, Harthan Jennifer S
École d'optométrie de l'Université de Montréal (L.M.), Montreal, Quebec, Canada; University of Missouri-St. Louis College of Optometry (E.S.B.), St. Louis, MO; Lake Havasu (S.L.W.), AZ; Illinois College of Optometry (R.R., J.S.H.), Chicago, IL; and Michigan College of Optometry (B.W.M., A.D.), Big Rapids, Michigan.
Eye Contact Lens. 2018 May;44(3):164-169. doi: 10.1097/ICL.0000000000000323.
This study aims to address the clinical performance of a large diameter rigid gas permeable lens (LRGP) in a group of subjects with low-to-moderate (0.75-2.75 D) refractive astigmatism. An additional goal was to determine whether soft toric or LRGP contact lenses performed better objectively in the correction of astigmatism and to determine which modality is preferred by subjects.
This was a multisite prospective cross-over clinical study. Ten asymptomatic contact lens wearers per site (four university clinics) were recruited and randomly assigned to group A or group B. Group A was assigned to start wearing Comfilcon A soft toric lens first, for two weeks, and then crossed over to LRGP lenses (Boston XO, 14.3 mm diameter miniscleral lens). Group B initially wore LRGP lenses and then crossed over to soft toric lenses. For each type of lens worn, low-contrast and high-contrast visual acuity (VA) were evaluated at distance. At the conclusion of the study, after two months, all subjects completed a questionnaire in which they were asked to indicate their preference for one type of lens (soft toric or LRGP) and to rate the quality of vision in day-to-day activities.
Thirty-six of 38 (94.7%) subjects completed the study with 75% preferring the vision of the LRGP lens as compared to the soft toric lenses worn in the study. 52.7% expressed a preference to continue with this modality despite only 38.8% reporting that these LRGP lenses are easy or very easy to handle. Wear time, subjective comfort, and subjective vision ratings exhibited no significant difference between the two groups.
In a population of asymptomatic contact lens wearers, LRGP lenses can be considered as a good alternative to soft toric lenses for the correction of refractive astigmatism.
本研究旨在探讨大直径硬性透气性镜片（LRGP）在一组低至中度（0.75 - 2.75 D）屈光性散光受试者中的临床性能。另一个目标是确定软性散光或LRGP隐形眼镜在散光矫正方面是否在客观上表现更好，并确定受试者更喜欢哪种方式。
这是一项多中心前瞻性交叉临床研究。每个研究地点（四个大学诊所）招募了10名无症状隐形眼镜佩戴者，并随机分配到A组或B组。A组首先佩戴Comfilcon A软性散光镜片两周，然后转换为LRGP镜片（波士顿XO，直径14.3 mm的迷你巩膜镜片）。B组最初佩戴LRGP镜片，然后转换为软性散光镜片。对于每种佩戴的镜片类型，在远距离评估低对比度和高对比度视力（VA）。在研究结束时，两个月后，所有受试者完成一份问卷，其中要求他们指出对一种镜片类型（软性散光或LRGP）的偏好，并对日常活动中的视力质量进行评分。
38名受试者中有36名（94.7%）完成了研究，与研究中佩戴的软性散光镜片相比，75%的受试者更喜欢LRGP镜片的视力。52.7%的人表示倾向于继续使用这种方式，尽管只有38.8%的人报告说这些LRGP镜片易于或非常易于操作。两组之间在佩戴时间、主观舒适度和主观视力评分方面没有显著差异。
在无症状隐形眼镜佩戴者群体中，LRGP镜片可被视为矫正屈光性散光的软性散光镜片的良好替代品。
