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橄榄油酚类化合物与神经保护

Olive oil phenols and neuroprotection.

机构信息

Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

Nutr Neurosci. 2013 Nov;16(6):243-9. doi: 10.1179/1476830513Y.0000000052. Epub 2013 Feb 11.

DOI:10.1179/1476830513Y.0000000052
PMID:23406576
Abstract

Olive oil is a rich source of phenolic components which have a wide variety of beneficial health effects in vitro, in vivo, and clinically. The beneficial effects of olive oil phenols attributed to a variety of biological activities including free radical scavenging/antioxidant actions, anti-inflammatory effects, anti-carcinogenic properties, and anti-microbial activities. On the other hand, olive oil phenols have been shown to be some of neuroprotective effects against cerebral ischemia, spinal cord injury, Huntington's disease, Alzheimer's diseases, multiple sclerosis, Parkinson's disease, aging, and peripheral neuropathy. This paper summarizes current knowledge on the mechanisms of neuroprotective effects of olive oil phenols.

摘要

橄榄油是酚类成分的丰富来源,具有多种有益的体外、体内和临床健康作用。橄榄油酚的有益作用归因于多种生物活性,包括自由基清除/抗氧化作用、抗炎作用、抗癌特性和抗微生物活性。另一方面,橄榄油酚已被证明具有一些神经保护作用,可对抗脑缺血、脊髓损伤、亨廷顿病、阿尔茨海默病、多发性硬化症、帕金森病、衰老和周围神经病。本文总结了橄榄油酚神经保护作用的机制的最新知识。

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