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扇形瓣叶在风湿性二尖瓣重建术中的应用。

Leaflet extension in rheumatic mitral valve reconstruction.

机构信息

Department of Cardiothoracic Surgery, National Heart Institute, Kuala Lumpur, Malaysia.

出版信息

Eur J Cardiothorac Surg. 2013 Oct;44(4):682-9. doi: 10.1093/ejcts/ezt035. Epub 2013 Feb 13.

Abstract

OBJECTIVES

Type IIIa mitral regurgitation (MR) due to rheumatic leaflet restriction often renders valve repair challenging and may predict a less successful repair. However, the utilization of leaflet mobilization and extension with the pericardium to increase the surface of coaptation may achieve satisfactory results. We reviewed our experience with leaflet extension in rheumatic mitral repair with emphasis on the technique and mid-term results.

METHODS

Between 2003 and 2010, 62 of 446 rheumatic patients had leaflet extension with glutaraldehyde-treated autologous pericardium as part of their mitral repair procedure. Their clinical and echocardiographic data were prospectively analysed.

RESULTS

The mean age of the rheumatic patients was 20.2 ± 11.7 years; range 3-60 years. Fourty-eight (77.4%) patients had predominant MR, while 22.6% had mixed mitral stenosis and mitral regurgitation (MS/MR). Leaflet extension was performed in the posterior, anterior and both leaflets in 77, 13 and 10% of patients, respectively. Additional repair procedures included neo-chordal replacement, chordal transfer/shortening/fenestration/resection, commissurotomy and papillary muscle splitting. All repairs were stabilized with annuloplasty rings. The follow-up was complete in all patients with a mean follow-up of 36.5 ± 25.6 months. There was no mortality in this series. At the latest follow-up, the MR grade was none/trivial in 64.5 of patients, mild in 22.6, moderate in 6.5, moderately severe in 4.8 and severe in 1.6%. Two patients had redo mitral surgery. At 5 years postoperatively, the estimated rates of freedom from reoperation and valve failure were 96.8 and 91.6%, respectively.

CONCLUSIONS

Repair with leaflet extension in rheumatic disease resulted in good early and mid-term outcomes. A wider utilization of this technique may increase the feasibility and durability of repair in complex rheumatic mitral valve disease.

摘要

目的

风湿性瓣叶限制导致的 IIIa 型二尖瓣反流(MR)常常使瓣叶修复具有挑战性,并且可能预示着修复效果不佳。然而,利用心包片来增加瓣叶对合面积的活动性和伸展性可能会获得满意的效果。我们回顾了风湿性二尖瓣修复中瓣叶延长的经验,重点介绍了该技术和中期结果。

方法

2003 年至 2010 年间,446 例风湿性心脏病患者中有 62 例采用戊二醛处理的自体心包作为二尖瓣修复术的一部分进行瓣叶延长。前瞻性分析了他们的临床和超声心动图数据。

结果

风湿性心脏病患者的平均年龄为 20.2 ± 11.7 岁;年龄范围 3-60 岁。48 例(77.4%)患者主要为 MR,22.6%患者为混合性二尖瓣狭窄伴二尖瓣反流(MS/MR)。77%、13%和 10%的患者分别在后瓣、前瓣和双瓣叶进行了瓣叶延长。附加的修复手术包括 neo-chordal 置换、腱索转移/缩短/开窗/切除、交界切开术和乳头肌切开术。所有修复均采用瓣环成形术稳定。所有患者均完成随访,平均随访时间为 36.5 ± 25.6 个月。该系列无死亡病例。在最近的随访中,64.5%的患者 MR 分级为无/轻度,22.6%为轻度,6.5%为中度,4.8%为中度重度,1.6%为重度。2 例患者行二尖瓣再次手术。术后 5 年,无再次手术和瓣膜失效的估计生存率分别为 96.8%和 91.6%。

结论

风湿性疾病瓣叶延长修复的早期和中期结果良好。更广泛地应用该技术可能会增加复杂风湿性二尖瓣疾病修复的可行性和耐久性。

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