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4D超声——关于脑瘫病因最新进展的医疗设备

4D Ultrasound - Medical Devices for Recent Advances on the Etiology of Cerebral Palsy.

作者信息

Tomasovic Sanja, Predojevic Maja

机构信息

Neurology Clinic, Clinical Hospital "Sveti Duh", Zagreb, Croatia.

出版信息

Acta Inform Med. 2011 Dec;19(4):228-34. doi: 10.5455/aim.2011.19.228-234.

Abstract

Children cerebral palsy (CCP) encompasses a group of nonprogessive and noninfectious conditions, which cause light, moderate, and severe deviations in neurological development. Diagnosis of CCP is set mostly by the age of 3 years. The fact that a large number of cerebral damage occurs prenatally and the fact that early intervention in cases of neurological damage is successful, prompted some researchers to explore the possibility of detecting neurologically damaged fetus in the uterus. This research was made possible thanks to the development of two-dimensional ultrasound technology in a real time, which enabled the display of the mobility of the fetus. Advancement of the ultrasound technology has enabled the development of 4D ultrasound where a spontaneous fetal movement can be observed almost in a real time. Estimate of the number and quality of spontaneous fetal movements and stitches on the head, the neurology thumb and a high palate were included in the prenatal neurological screening of the fetus. This raises the question, as to does the fetal behavior reflect, (which was revealed in 2D or 4D ultrasound), fetal neurological development in a manner that will allow the detection of the brain damage.

摘要

儿童脑瘫(CCP)包括一组非进行性和非传染性疾病,这些疾病会导致神经发育出现轻度、中度和重度偏差。CCP的诊断大多在3岁时确定。大量脑损伤发生在产前这一事实,以及神经损伤病例早期干预取得成功这一事实,促使一些研究人员探索在子宫内检测神经受损胎儿的可能性。由于实时二维超声技术的发展,这项研究成为可能,该技术能够显示胎儿的活动情况。超声技术的进步使得4D超声得以发展,几乎可以实时观察到胎儿的自发运动。胎儿自发运动的数量和质量估计以及头部、神经学拇指和高腭部的缝线情况被纳入胎儿产前神经筛查。这就引发了一个问题,即(在二维或四维超声中显示的)胎儿行为是否以一种能够检测出脑损伤的方式反映胎儿神经发育情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49bb/3564175/807ec9df7294/AIM-19-228_F1.jpg

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