Tomasović S, Predojević M
Acta Med Croatica. 2015;69(5):415-20.
Neurodevelopment disorders including cerebral palsy are a group of non-progressive and noninfectious diseases characterized by different levels of abnormal neurodevelopment. Most often, diagnosis is made at the age of 5 years or later. It has been recognized that most of the cerebral damages appear prenatally. This fact stimulated researchers all over the world to detect the possible causes in utero. These studies have been possible due to the development of ultrasound technology in real time and display of fetal mobility. Thanks to the development of four-dimensional (4D) ultrasound, prenatal screening neurological test was developed. The test is based on assessment of the number and quality of spontaneous movements of the fetus. The question arises whether fetal behavior, observed on 4D ultrasound, reflects neurological development of the fetus in a manner that will allow detection of brain damage in utero.
包括脑瘫在内的神经发育障碍是一组非进行性和非传染性疾病，其特征是神经发育异常程度不同。大多数情况下，诊断是在5岁或更晚的时候做出的。人们已经认识到，大多数脑损伤发生在产前。这一事实促使世界各地的研究人员去探寻子宫内可能的病因。由于实时超声技术的发展以及胎儿活动的显示，这些研究得以开展。得益于四维（4D）超声的发展，产前筛查神经学检测得以开发。该检测基于对胎儿自发运动的数量和质量的评估。问题在于，通过4D超声观察到的胎儿行为是否能以一种有助于在子宫内检测脑损伤的方式反映胎儿的神经发育情况。
