Bhavani Nisha, Praveen Valiyaparambil Pavithran, Jayakumar Rohinivilasam Vasukutty, Nair Vasantha, Muraleedharan Mangath, Kuma Harish, Unnikrishnan Ambika Gopalakrishnan, Menon Vadayath Usha
Department of Endocrinology and Diabetes, Amrita Institute of Medical Sciences, Cochin 682041, Kerala, India.
J Assoc Physicians India. 2012 Jun;60:52-4.
We report a cse of nephrocalcinosis with renal failure which on evaluation was found to have hypercalcemia. Further investigations showed an inappropriately normal intact parathormone (iPTH) and 1,25 dihydroxy-vitamin D level in the setting of renal failure. Probing for a cause of non-PTH mediated hypercalcemia led to the diagnosis of sarcoidosis. Treatment with glucocorticoids could partially reverse the renal failure and control the hypercalcemia. This case illustrates the importance of careful interpretation of laboratory parameters especially levels of iPTH and vitamin D metabolites in renal failure.
我们报告一例伴有肾衰竭的肾钙质沉着症病例,经评估发现存在高钙血症。进一步检查显示,在肾衰竭情况下,完整甲状旁腺激素(iPTH)和1,25-二羟维生素D水平异常正常。对非甲状旁腺激素介导的高钙血症病因进行探究后,诊断为结节病。糖皮质激素治疗可部分逆转肾衰竭并控制高钙血症。该病例说明了在肾衰竭中仔细解读实验室参数尤其是iPTH和维生素D代谢产物水平的重要性。