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骨移植供体部位医源性巨细胞瘤植入及预防“一种罕见可避免并发症”的临床建议

Iatrogenic implantation of giant cell tumor at bone graft donor site and clinical recommendations to prevent "a rare avoidable complication".

作者信息

Gulia Ashish, Puri Ajay, Salunke Abhijeet, Desai Subhash, Jambhekar N A

机构信息

Orthopedic Oncology, Room no: 27, Bone and Soft Tissue Services, Tata Memorial Hospital, E. Borges Marg, Parel, Mumbai 400012, Maharashtra, India.

出版信息

Eur J Orthop Surg Traumatol. 2013 Aug;23(6):715-8. doi: 10.1007/s00590-012-1055-3. Epub 2012 Aug 8.

Abstract

The treatment of giant cell tumor of bone is directed toward local control without sacrificing joint function. This is achieved by intralesional curettage. When autograft is used for the reconstruction of the curetted cavity, there is always a theoretical risk of contamination of graft donor site. We report a case of iatrogenic implantation of giant cell tumor at the bone graft donor site after intralesional curettage and bone grafting of giant cell tumor of distal femur. Patient was treated with repeat intralesional curettage and excision of implantation lesion at bone graft donor site. We recommend precautionary measures to prevent this avoidable complication.

摘要

骨巨细胞瘤的治疗旨在实现局部控制而不牺牲关节功能。这通过病灶内刮除术来实现。当使用自体骨移植来重建刮除后的骨腔时,移植供区总是存在理论上的污染风险。我们报告了1例在股骨远端骨巨细胞瘤病灶内刮除及骨移植后,骨移植供区发生医源性骨巨细胞瘤种植的病例。患者接受了重复病灶内刮除及骨移植供区种植病灶切除术。我们建议采取预防措施以防止这种可避免的并发症。

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