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影响髋部骨折手术后死亡率的因素:对578例患者的回顾性分析。

Factors affecting mortality after hip fracture surgery: a retrospective analysis of 578 patients.

作者信息

Bilsel Kerem, Erdil Mehmet, Gulabi Deniz, Elmadag Mehmet, Cengiz Omer, Sen Cengiz

机构信息

Orthopaedic and Traumatology Department, Bezmialem Vakif University, 34093, Fatih, Istanbul, Turkey,

出版信息

Eur J Orthop Surg Traumatol. 2013 Dec;23(8):895-900. doi: 10.1007/s00590-012-1104-y. Epub 2012 Oct 16.

Abstract

PURPOSE

To determine the effect of patient and surgical factors on mortality after hip fracture surgery.

DESIGN

Retrospective study.

SETTING

Level-one trauma and tertiary referral centers.

METHODS

Patients were eligible if they were aged 65 years or older and had undergone surgery for a non-pathological femoral neck or intertrochanteric hip fracture between 2008 and 2011. The primary outcome was mortality: within the first year after surgery, after the first year, and survival as of the last questioning date. Of the 578 eligible patients, 399 (69%) were women; mean age was 79 years; and mean follow-up was 17 months.

RESULTS

Mortality during the first year was significantly more frequent in patients aged 80 years or older (67 vs. 33%; P < 0.001). Estimated overall survival was significantly longer in women (43 vs. 37%; P = 0.01). The type of fracture had no impact on mortality (P = 0.96). Patients with high ASA class had a significant effect on mortality (P < 0.001). Surgery timing did not affect mortality in univariate analysis (P = 0.25). The mortality rate for hemiarthroplasty was higher than osteosynthesis options (P = 0.03). The effect of the type of anesthesia on mortality was not significant (P = 0.74).

CONCLUSIONS

Older men had the highest risk of mortality within the first year. Patients with ASA ratings of class 3 or 4 need to be evaluated carefully because they appear to be at higher risk of early mortality. Osteosynthesis has a lower mortality than does arthroplasty for hip fracture and thus should be preferred if either treatment is possible.

LEVEL OF EVIDENCE

IV.

摘要

目的

确定患者因素和手术因素对髋部骨折手术后死亡率的影响。

设计

回顾性研究。

地点

一级创伤中心和三级转诊中心。

方法

年龄在65岁及以上、于2008年至2011年间接受非病理性股骨颈或转子间髋部骨折手术的患者符合入选标准。主要结局为死亡率:术后第一年内、第一年后以及截至最后一次随访日期的生存率。在578例符合条件的患者中,399例(69%)为女性;平均年龄为79岁;平均随访时间为17个月。

结果

80岁及以上患者在术后第一年内的死亡率显著更高(67%对33%;P<0.001)。女性的估计总生存率显著更长(43%对37%;P = 0.01)。骨折类型对死亡率无影响(P = 0.96)。美国麻醉医师协会(ASA)分级高的患者对死亡率有显著影响(P<0.001)。单因素分析中手术时机不影响死亡率(P = 0.25)。半关节成形术的死亡率高于骨固定术(P = 0.03)。麻醉类型对死亡率的影响不显著(P = 0.74)。

结论

老年男性在术后第一年内的死亡风险最高。ASA分级为3级或4级的患者需要仔细评估,因为他们似乎早期死亡风险更高。对于髋部骨折,骨固定术的死亡率低于关节成形术,因此如果两种治疗方法都可行,应优先选择骨固定术。

证据级别

IV级。

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