干预槟榔咀嚼习惯对口腔黏膜下纤维化发病率的影响。
Effect on the incidence of oral submucous fibrosis of intervention in the areca nut chewing habit.
作者信息
Murti P R, Gupta P C, Bhonsle R B, Daftary D K, Mehta F S, Pindborg J J
机构信息
Basic Dental Research Unit, Tata Institute of Fundamental Research, Bombay, India.
出版信息
J Oral Pathol Med. 1990 Feb;19(2):99-100. doi: 10.1111/j.1600-0714.1990.tb00805.x.
Incidence of oral submucous fibrosis was calculated from a 10-yr prospective intervention study of 12,212 individuals with a strong component of health education on tobacco and area nut chewing. Based on 11 new cases among 6341 chewers, the annual incidence was 8.0 per 100,000 among men and 29.0 for women. An earlier 10-yr follow-up study, with no intervention component, served as control. Based on 11 new cases among 3,809 chewers, the annual incidence was 21.3 per 100,000 for men and 45.7 for women controls. Although the decrease in the incidence in the intervention cohort was not statistically significant due to small number of cases, the results underscored the causal role of areca nut chewing and indicated the potential for primary prevention of oral submucous fibrosis.
口腔黏膜下纤维化的发病率是根据一项对12212人进行的为期10年的前瞻性干预研究计算得出的，该研究有关于烟草和槟榔咀嚼的强有力的健康教育内容。在6341名咀嚼者中有11例新发病例，男性的年发病率为每10万人8.0例，女性为29.0例。一项早期的为期10年的随访研究（无干预内容）用作对照。在3809名咀嚼者中有11例新发病例，男性对照的年发病率为每10万人21.3例，女性对照为45.7例。尽管由于病例数少，干预队列中发病率的下降没有统计学意义，但结果强调了槟榔咀嚼的因果作用，并表明了口腔黏膜下纤维化一级预防的潜力。
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