Submucous fibrosis in Taiwan.

Thirty-five cases of submucous fibrosis have been collected in Taiwan. The fibrotic changes occurred most often in the buccal and palatal mucosa, and between the ages of 30 and 50 years. The occurrence of the disease correlated highly with the habit of betel nut chewing. Tobacco, hot spicy foods, and liquor were not important etiologic factors.