Büyükkapu-Bay Sema, Akça Ahmet, Karadoğan Meriban, Çorapçioğlu Funda, Anik Yonca
1Department of Pediatrics, Kocaeli University School of Medicine, Kocaeli, Turkey.
J Child Neurol. 2014 Mar;29(3):385-8. doi: 10.1177/0883073812475157. Epub 2013 Feb 17.
A patient with neurofibromatosis type 1 and the rare finding of concomitant meningioma and optic pathway glioma within the same optic nerve is presented. A 4-year-old boy was admitted to our hospital with right-sided proptosis. He also had numerous café-au-lait macules and axillary freckling on physical exam. According to National Institutes of Health (NIH) criteria, he met the diagnostic criteria for neurofibromatosis type 1. On magnetic resonance imaging (MRI), a mass originating from the right optic nerve sheath with normal appearance of the optic nerve was observed, which was consistent with optic nerve sheath meningioma. Another mass lesion was observed in the prechiasmatic region of the same optic nerve, which was consistent with optic nerve glioma. Two different types of optic pathway tumors in the same optic nerve is an extraordinary case. It is important to recognize imaging findings of these tumors and make correct diagnosis.
本文报告了1例1型神经纤维瘤病患者，其罕见地在同一视神经内同时伴有脑膜瘤和视路胶质瘤。一名4岁男孩因右侧眼球突出入院。体格检查发现他还有大量咖啡牛奶斑和腋窝雀斑。根据美国国立卫生研究院（NIH）标准，他符合1型神经纤维瘤病的诊断标准。磁共振成像（MRI）显示，起源于右侧视神经鞘且视神经外观正常的肿块，符合视神经鞘脑膜瘤。在同一视神经的视交叉前区还观察到另一个肿块病变，符合视神经胶质瘤。同一视神经内出现两种不同类型的视路肿瘤是一种特殊情况。认识这些肿瘤的影像学表现并做出正确诊断很重要。
