Parker Richard T, Ovens Christopher A, Fraser Clare L, Samarawickrama Chameen
Sydney Medical School, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Sydney, NSW, Australia,
Save Sight Institute, University of Sydney, Sydney, NSW, Australia.
Eye Brain. 2018 Oct 24;10:85-99. doi: 10.2147/EB.S144345. eCollection 2018.
Optic nerve sheath meningiomas are rare benign neoplasms of the meninges surrounding the optic nerve. They are a significant cause of morbidity. While the mortality rate is practically zero, these tumors can blind or disfigure patients. Given that the clinical course can be variable, and treatment has the capacity to cause morbidity itself, the management of these patients can be difficult. We review the literature to discuss the prevalence of optic nerve sheath meningiomas, the association with neurofibromatosis type 2, natural history, and management options and strategies.
视神经鞘膜脑膜瘤是围绕视神经的脑膜的罕见良性肿瘤。它们是导致发病的重要原因。虽然死亡率几乎为零，但这些肿瘤可导致患者失明或毁容。鉴于临床病程可能多变，且治疗本身也可能导致发病，因此对这些患者的管理可能很困难。我们回顾文献以讨论视神经鞘膜脑膜瘤的患病率、与2型神经纤维瘤病的关联、自然病程以及管理选项和策略。
