Rahimy Ehsan, Sarraf David
Jules Stein Eye Institute, University of California, Los Angeles, CA 90095, USA.
Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr;44(2):187-9. doi: 10.3928/23258160-20130212-02. Epub 2013 Feb 19.
The authors report a case of nanoparticle albumin-bound paclitaxel-induced cystoid macular edema (CME) without fluorescein angiographic leakage in a patient being treated for metastatic breast cancer. The CME briskly improved 3 weeks after the chemotherapeutic agent was discontinued and was completely resolved after 6 weeks. Patients receiving taxane therapy must be counseled to report any vision problems during their treatment period because early recognition of this rare but severe adverse event can facilitate appropriate intervention to reverse visual compromise and minimize any potential long-term ophthalmologic sequelae.
作者报告了一例在接受转移性乳腺癌治疗的患者中，纳米白蛋白结合型紫杉醇引起的黄斑囊样水肿（CME），且荧光素血管造影无渗漏。在停用化疗药物3周后，CME迅速改善，并在6周后完全消退。必须建议接受紫杉烷治疗的患者在治疗期间报告任何视力问题，因为尽早识别这种罕见但严重的不良事件有助于进行适当干预，以扭转视力损害并将任何潜在的长期眼科后遗症降至最低。
